Does Social Buffering Continue to be Effective Over the Peripubertal Period When Friends Share the Stressor Experience?

Sponsor
University of Minnesota (Other)
Overall Status
Recruiting
CT.gov ID
NCT04311996
Collaborator
(none)
200
1
4
35.2
5.7

Study Details

Study Description

Brief Summary

The purpose of this experiment is to determine whether social buffering by friends of stress physiology remains effective later in puberty when friends share the load versus when they provide support but are not undergoing the stressor with the target child. There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

Condition or Disease Intervention/Treatment Phase
  • Other: Questionnaires
  • Other: TSST
N/A

Detailed Description

Adolescents experience social evaluation stress frequently. However, it is likely that often they are not alone, but with friends who are also going through the same experience. Thus, it is possible that under these conditions, social buffering by friends does not wane over the peripubertal period. Participants will be assigned to social conditions while engaging in an evaluative stressor task.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
200 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
Does Social Buffering Continue to be Effective Over the Peripubertal Period When Friends Share the Stressor Experience?
Actual Study Start Date :
Oct 25, 2021
Anticipated Primary Completion Date :
Oct 1, 2024
Anticipated Study Completion Date :
Oct 1, 2024

Arms and Interventions

Arm Intervention/Treatment
Experimental: Friend and Target Both

There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

Other: Questionnaires
The participant will complete questionnaires, including ones on pubertal development and quality of relations with parents and friends.

Other: TSST
Participants will, via an online session, complete the TSST which is a standardized speech & math performance known to elicit a cortisol stress response.
Other Names:
  • Trier Social Stress Test
  • Experimental: Friend Provides Support

    There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

    Other: Questionnaires
    The participant will complete questionnaires, including ones on pubertal development and quality of relations with parents and friends.

    Other: TSST
    Participants will, via an online session, complete the TSST which is a standardized speech & math performance known to elicit a cortisol stress response.
    Other Names:
  • Trier Social Stress Test
  • Experimental: Unfamiliar Peer and Target

    There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

    Other: Questionnaires
    The participant will complete questionnaires, including ones on pubertal development and quality of relations with parents and friends.

    Other: TSST
    Participants will, via an online session, complete the TSST which is a standardized speech & math performance known to elicit a cortisol stress response.
    Other Names:
  • Trier Social Stress Test
  • Experimental: Alone

    There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

    Other: Questionnaires
    The participant will complete questionnaires, including ones on pubertal development and quality of relations with parents and friends.

    Other: TSST
    Participants will, via an online session, complete the TSST which is a standardized speech & math performance known to elicit a cortisol stress response.
    Other Names:
  • Trier Social Stress Test
  • Outcome Measures

    Primary Outcome Measures

    1. Change in Cortisol AUCi [2 hours]

      8 samples will be taken during the course of the assessment. Area under the curve from initial (baseline) will be calculated and used in the analyses.

    2. Change in salivary Alpha Amylase, AUCi [2 hours]

      salivary Alpha Amylase is used to index autonomic/sympathetic function. From 3 of the saliva samples already taken during the course of the assessment, alpha amylase will be determined by assay. Area under the curve will be calculated during periods of stress (social evaluation) and non-stress (no evaluation) during the course of the assessment. Outcome is reported as the difference between condition scores.

    Secondary Outcome Measures

    1. Self Report of Stress [2 hours]

      The Self Report of Stress is an 8-item questionnaire assessing participant level of stress at various time points across the session. Items are rated on a 5 point Likert scale. Total score is the unweighted mean of item scores. Total scores range from 0 to 40, with higher scores indicating greater stress. The assessment will be administered at baseline (no stress) and during a period of stress. The outcome will be reported as the difference between the baseline period and experimental stress period.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    11 Years to 14 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • sufficient vision, hearing, and language skills to provide verbal and written assent

    • ability to see and read stimuli presented on the computer screen

    • ability to hear verbal instructions provided by the experimenter and judges

    Exclusion Criteria:
    • premature birth (less than 37 weeks)

    • congenital and/or chromosomal disorders (e.g. cerebral palsy, FAS, mental retardation, Turner Syndrome, Down Syndrome, Fragile X)

    • Autism Spectrum Disorders

    • history of serious medical illness (e.g., cancer, organ transplant)

    • serious psychiatric illness

    • systemic glucocorticoids or beta-adrenergic medication use

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 University of Minnesota Minneapolis Minnesota United States 55455

    Sponsors and Collaborators

    • University of Minnesota

    Investigators

    • Principal Investigator: Megan Gunnar, PhD, University of Minnesota
    • Principal Investigator: Kathleen Thomas, PhD, University of Minnesota

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University of Minnesota
    ClinicalTrials.gov Identifier:
    NCT04311996
    Other Study ID Numbers:
    • STUDY00006378-3
    First Posted:
    Mar 17, 2020
    Last Update Posted:
    Mar 14, 2022
    Last Verified:
    Feb 1, 2022
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No

    Study Results

    No Results Posted as of Mar 14, 2022