Factors Affecting Hand Dysfunction in Patient With Rheumatoid Arthritis and Its Correlation With Quality of Life

Sponsor

Assiut University (Other)

Overall Status

Unknown status

CT.gov ID

NCT03274570

Collaborator

(none)

100

Enrollment

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

The aims of the research are:

To predict factors affecting hand dysfunction in patient with rheumatoid arthritis
To study the effect of hand dysfunction on quality of life in patient with rheumatoid arthritis

Condition or Disease	Intervention/Treatment	Phase
Rheumatoid Arthritis

Detailed Description

Rheumatoid Arthritis (RA) is the most common chronic autoimmune systemic inflammatory arthritis, associated with considerable impairments of Quality of life .

Hand is the principle means by which an individual interacts with people and objects in the external environment .Many factors affect hand function in addition to arthritis ,. Many RA patients suffer from an increased loss of muscle mass with a significant impact on these patients' quality of life , and also Distal sensory, mixed sensorimotor, mononeuritis multiplex and entrapment neuropathy are the most commonly reported types of neuropathy in RA .So assessment of factors causing hand dysfunction can provide us a quick and early insight on the debilitating effects of RA on functioning and disability.Thus Early intervention can then be initiated which will help limit joint damage and thereby improve functional outcomes.

Study Design

Study Type:

Observational

Anticipated Enrollment :

100 participants

Observational Model:

Case-Only

Time Perspective:

Cross-Sectional

Official Title:

Factors Affecting Hand Dysfunction in Patient With Rheumatoid Arthritis and Its Correlation With Quality of Life

Anticipated Study Start Date :

Oct 1, 2017

Anticipated Primary Completion Date :

Oct 30, 2018

Anticipated Study Completion Date :

Jan 31, 2019

Outcome Measures

Primary Outcome Measures

quality of life [one year]
Health assessment questionnaire disability index (HAQ)

Secondary Outcome Measures

hand function [one year]
measured by musculoskeletal ultrasound

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Adult Patients who fulfilled the American College of Rheumatology (ACR) (2010) criteria for RA, attending the Rheumatology and Rehabilitation outpatient clinic and in-patient department, Faculty of Medicine, Assuit University Hospitals.

Exclusion Criteria:

Patients with other rheumatic diseases.
Patients less than 18 years old.
Patients with co-morbidities influencing disease activity and hand function (e.g., end- stage liver or renal disease, serious infections, or severe cardiac, respiratory, gastrointestinal disease) .
Patient with any recent history of hand trauma, or surgery.
Patient with neurological involvement as , peripheral neuropathy and radiculopathy

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Assiut University

Investigators

Study Director: Safaa A Mahran, professor, Assiut University
Study Director: Essam Abda, professor, Assiut University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Essraa Mohammed, Principal Investigator, Assiut University

ClinicalTrials.gov Identifier:

NCT03274570

Other Study ID Numbers:

Hand function in RA

First Posted:

Sep 7, 2017

Last Update Posted:

Sep 7, 2017

Last Verified:

Aug 1, 2017

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Arthritis

Arthritis, Rheumatoid

Study Results

No Results Posted as of Sep 7, 2017