Age and Refraction in Predicting Myopia Progression in COVID-19
Study Details
Study Description
Brief Summary
To determine the longitudinal changes of age and refraction in predicting myopia progression with risk under the coronavirus disease 2019 (COVID-19) pandemic in a 3-year follow-up of a Chinese cohort.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
This was part of the large-scale Tianjin Eye Study, a population-based cohort study that longitudinally investigates the relationship between the age, refraction, and development of childhood RE in Tianjin, China.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| 2019 screening 34,400 schoolchildren with a 36-month follow-up from 2019 to 2021. |
Other: screening
This study included 34,400 students, as part of the Tianjin Eye Study who performed a 3-year follow-up from 2019 to 2021. All participants underwent yearly noncycloplegic refraction and ocular examinations. Time-related changes in sphere, cylinder, and spherical equivalent (SE) measurements in both sexes were analyzed.
|
| 2020 screening 34,400 schoolchildren with a 36-month follow-up from 2019 to 2021. |
Other: screening
This study included 34,400 students, as part of the Tianjin Eye Study who performed a 3-year follow-up from 2019 to 2021. All participants underwent yearly noncycloplegic refraction and ocular examinations. Time-related changes in sphere, cylinder, and spherical equivalent (SE) measurements in both sexes were analyzed.
|
| 2021 screening 34,400 schoolchildren with a 36-month follow-up from 2019 to 2021. |
Other: screening
This study included 34,400 students, as part of the Tianjin Eye Study who performed a 3-year follow-up from 2019 to 2021. All participants underwent yearly noncycloplegic refraction and ocular examinations. Time-related changes in sphere, cylinder, and spherical equivalent (SE) measurements in both sexes were analyzed.
|
Outcome Measures
Primary Outcome Measures
- changes of sphere [change from baseline at 36 months]
changes of sphere
- changes of cylinder [change from baseline at 36 months]
changes of cylinder
- changes of spherical equivalent [change from baseline at 36 months]
changes of spherical equivalent
- changes and distribution of visual acuity [change from baseline at 36 months]
changes and distribution of visual acuity
Eligibility Criteria
Criteria
Inclusion Criteria:
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no concurrent eye disease;
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age 6-15 years.
Exclusion Criteria:
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significant systemic illnesses
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ocular conditions that could affect the corneal curvature, including congenital corneal diseases,
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pterygium, keratoconus, other corneal degeneration or dystrophy conditions,
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media opacity, uveitis, glaucoma
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a history of intraocular surgery, refractive surgery,
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neurologic or retinal diseases, current corneal refractive therapy (ortho-K),
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low-dose atropine therapy for myopia control
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Tianjin Eye Hospital | Tianjin | China | 300020 |
Sponsors and Collaborators
- Tianjin Eye Hospital
Investigators
- Study Chair: Yan Wang, director, Tianjin Eye Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
- Hu Y, Zhao F, Ding X, Zhang S, Li Z, Guo Y, Feng Z, Tang X, Li Q, Guo L, Lu C, Yang X, He M. Rates of Myopia Development in Young Chinese Schoolchildren During the Outbreak of COVID-19. JAMA Ophthalmol. 2021 Oct 1;139(10):1115-1121. doi: 10.1001/jamaophthalmol.2021.3563. Erratum in: JAMA Ophthalmol. 2021 Oct 21;:.
- Ma D, Wei S, Li SM, Yang X, Cao K, Hu J, Fan S, Zhang L, Wang N. Progression of myopia in a natural cohort of Chinese children during COVID-19 pandemic. Graefes Arch Clin Exp Ophthalmol. 2021 Sep;259(9):2813-2820. doi: 10.1007/s00417-021-05305-x. Epub 2021 Jul 21.
- 2022018