Detection of Topographic Residual Acuity in Patients With Age Related Macular Degeneration

• Sponsor: University Health Network, Toronto (Other)
• Overall Status: Completed
• CT.gov ID: NCT00329277
• Collaborator: (none)
• Enrollment: 30
• Location: 1
• Duration (Months): 21
• Patients Per Site Per Month: 1.4

Study Details

Study Description

Brief Summary

Standard perimetry provides information on topographical retinal sensitivity to light stimuli, however the said locus is not necessarily the preferred locus for fixation. Standard perimetry could also be used as a way for macular scotoma mapping, indirectly showing the fixation locus. Topographic acuity at the preferred retinal locus can be determined if correlation between loci with high sensitivity, eccentric fixation loci and potential visual acuity measurements are correlated.

PURPOSE OF THE STUDY:

Determination of visual acuity at preferred retinal locus in Low Vision patients with ARMD using eye standard automated and computerized perimetry methods.

Condition or Disease	Intervention/Treatment	Phase
Age-Related Macular Degeneration	Procedure: perimetry	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 30 participants
• Allocation: Non-Randomized
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Diagnostic
• Study Start Date: Apr 1, 2006
• Actual Primary Completion Date: Jan 1, 2008
• Actual Study Completion Date: Jan 1, 2008

Outcome Measures

Primary Outcome Measures

1. Location of eccentric retinal locus of highest fixation accuracy []

Secondary Outcome Measures

1. Location of eccentric locus with best retinal sensitivity []

Eligibility Criteria

Criteria

• Ages Eligible for Study: N/A and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• AMD with documented pathology

• Low Vision both eyes

• BCVA 20/50-20/400 in best eye

Exclusion Criteria:

• Cognitive impairment

• Other retinal pathology

• Previous retinal surgery

• Significant media opacity

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Dr S N Markowitz	Toronto	Ontario	Canada	M6H 2H1

Sponsors and Collaborators

• University Health Network, Toronto

Investigators

• Principal Investigator: Samuel Markowitz, MD, University Health Network, Toronto

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• ClinicalTrials.gov Identifier: NCT00329277
• Other Study ID Numbers: SNM200601
• First Posted: May 24, 2006
• Last Update Posted: May 28, 2008
• Last Verified: Nov 1, 2006

• Keywords provided by , ,: age-related macular degeneration; preferred retinal locus; macular perimetry
• Additional relevant MeSH terms: Macular Degeneration

Study Results

No Results Posted as of May 28, 2008