Short-term Postural Training for Older Adults

Sponsor
National Cheng-Kung University Hospital (Other)
Overall Status
Recruiting
CT.gov ID
NCT04137952
Collaborator
Ministry of Science and Technology, Taiwan (Other)
150
1
3
41
3.7

Study Details

Study Description

Brief Summary

Generalization refers to skill transfer under various working spaces following motor practice. The extent of generalization effect links causal to in-depth recognition of error properties during motor practice. Idiom says "imperfect practice makes perfect". It could be beneficial for the elderly to gain superior capacity of balance transfer skill under the short-term productive failure learning environments. In contrast to traditional visual feedback that uses error avoidance training to optimize target balance task, the present 3-year proposal is to propose three potential neuro-cognitive strategies to improve motor skill transfer following stabilometer training. The strategies are expected to enhance opportunities of error experience and motor exploration via modified visual feedback, underlying facilitations of attentional resource and error-related neural networks. In the first year, the neuro-cognitive strategy for balance practice is progressive augmentation of visual error size to improve balance skill transfer. In the second year, the neuro-cognitive strategy for balance practice is visual feedback with virtual uncertainness of motor goal. In the third year, the neuro-cognitive strategy for balance practice is stroboscopic vision. EEG and central of pressure will be processed with non-linear approaches. Graph theory will characterize EEG functional connectivity and brain network efficiency regarding to brain mechanisms for practice-related leaning transfer. Trajectories of central of pressure will be analyzed with stabilogram diffusion analysis to reveal behavior mechanisms for practice-related variations in feedback and feedforward process for error corrections.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: size of error visual feedback
N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
150 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
The Use of Neuro-cognitive Strategies to Power Generalization Effect After Short-term Postural Training for Older Adults
Actual Study Start Date :
Aug 1, 2019
Anticipated Primary Completion Date :
Dec 30, 2022
Anticipated Study Completion Date :
Dec 30, 2022

Arms and Interventions

Arm Intervention/Treatment
Experimental: deterministic visual error gain

Day1(Pretest): stabilometer stance, 3 times/1 min air pillow stance, 3 time/30 sec poture-supraposture dual task, 3 times/1 min Day2 to Day5: Exp.group:27 times of posture tracking with high visual error gain. Control group:27 times of posture training with normal visual error gain. Day6 (Posttest): stabilometer stance, 3 times/1 min air pillow stance, 3 time/30 sec poture-supraposture dual task, 3 times/1 min

Behavioral: size of error visual feedback
The strategies are expected to enhance opportunities of error experience and motor exploration via modified visual feedback, underlying facilitations of attentional resource and error-related neural networks.
Other Names:
  • virtual uncertainness of motor goals
  • stroboscopic vision
  • Experimental: stochastic visual noise

    Day1(Pretest): stabilometer stance, 3 times/1 min air pillow stance, 3 time/30 sec poture-supraposture dual task, 3 times/1 min Day2 to Day5: Exp.group A:27 times of posture training with posture tracking signal-to-noise ratio=2:1. Exp.group B:27 times of posture training with posture tracking signal-to-noise ratio=4:1. Control group:27 times of posture training with normal visual error gain. Day6(Posttest): stabilometer stance, 3 times/1 min air pillow stance, 3 time/30 sec poture-supraposture dual task, 3 times/1 min

    Behavioral: size of error visual feedback
    The strategies are expected to enhance opportunities of error experience and motor exploration via modified visual feedback, underlying facilitations of attentional resource and error-related neural networks.
    Other Names:
  • virtual uncertainness of motor goals
  • stroboscopic vision
  • Experimental: intermittent visual gain

    Day1 (Pretest): stabilometer stance with wearing flash glasses (low frequency with opaque ratio 50%), 4 times/45 sec stabilometer stance with wearing flash glasses (high frequency with opaque ratio 50%), 4 times/45 sec. stabilometer stance with wearing flash glasses (clear), 4 times/45 sec air pillow stance, 8 times/1 min Day2 (training section): Exp. group:Posture tracking with wearing flash glasses (low frequency with opaque ratio 50%), 12 times/45 sec. Control group:Posture tracking with wearing flash glasses (clear), 12 times/45 sec. Day3 (Posttest): stabilometer stance with wearing flash glasses (low frequency with opaque ratio 50%), 4 times/45 sec stabilometer stance with wearing flash glasses (high frequency with opaque ratio 50%), 4 times/45 sec stabilometer stance with wearing flash glasses (clear), 4 times/45 sec air pillow stance, 8 times/1 min

    Behavioral: size of error visual feedback
    The strategies are expected to enhance opportunities of error experience and motor exploration via modified visual feedback, underlying facilitations of attentional resource and error-related neural networks.
    Other Names:
  • virtual uncertainness of motor goals
  • stroboscopic vision
  • Outcome Measures

    Primary Outcome Measures

    1. EEG graph analysis [through study completion, an average of 1 year]

      Graph theory will characterize EEG functional connectivity and brain network efficiency regarding to brain mechanisms for practice-related leaning transfer.

    Secondary Outcome Measures

    1. stabilogram diffusion analysis of central of pressure [through study completion, an average of 1 year]

      Trajectories of central of pressure will be analyzed with stabilogram diffusion analysis to reveal behavior mechanisms for practice-related variations in feedback and feedforward process for error corrections.

    2. root mean sqaure error of stabilometer [through study completion, an average of 1 year]

      The root-mean-square value of the tracking trajectory of stabilometer and the target signal.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    60 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Age above 60 years old healthy older adults without a history of falls.

    • Able to understand and give informed consent.

    • The Mini-Mental State Examination test score above 25-30.

    • Lower limb muscle strength is evaluated as G grade

    • The corrected visual acuity was within the normal range.

    Exclusion Criteria:
    • Any known history of mental illness

    • Any neuromuscular or degenerative neurological disease(ex:stroke、SCI、TBI...etc)

    • Any known history of cerebral cerebellar disease or intracranial metal implants.

    • Weak of hearing or wearing a hearing aid

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 National Chen Kong University Hospital Taian Eastern District Taiwan 701

    Sponsors and Collaborators

    • National Cheng-Kung University Hospital
    • Ministry of Science and Technology, Taiwan

    Investigators

    • Study Chair: Hwang Ing-Shiou, Phd, NCKU, Institute of Allied Health Sciences

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    National Cheng-Kung University Hospital
    ClinicalTrials.gov Identifier:
    NCT04137952
    Other Study ID Numbers:
    • MOST 108-2314-B-006-071 -
    First Posted:
    Oct 24, 2019
    Last Update Posted:
    Jun 8, 2021
    Last Verified:
    Jun 1, 2021
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by National Cheng-Kung University Hospital

    Study Results

    No Results Posted as of Jun 8, 2021