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SWEET: Frequency of Aerobic/Resistance Training in Older Women

Sponsor
University of Alabama at Birmingham (Other)
Overall Status
Completed
CT.gov ID
NCT01031394
Collaborator
National Institute on Aging (NIA) (NIH)
105
Enrollment
1
Location
3
Arms
85.9
Duration (Months)
1.2
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The objective of this study is to provide insight into the effects combined training frequency has on improving fitness, ease of physical activity, and maintenance of a high total energy expenditure. Such information is critical to our understanding of ways to improve well-being, quality of life, and independence of an aging population. 105 participants will be enrolled in this study. The length of time for your involvement in the study will be 32 weeks. You will undergo the procedures listed in this consent form on 3 separate occasions-initially at your entry, at 16 weeks and again at 32 weeks.

Condition or Disease Intervention/Treatment Phase
  • Other: Frequency of Aerobic/Resistance Training - 3 to 3
 N/A

Detailed Description

Frequency of aerobic/resistance training in older women

Abstract Combined aerobic and resistance training have unique benefits for maintaining a physical activity (PA). However, the optimal training program for combining these two modes of training in older adults is unknown. This study builds on current and past studies showing that training induced gains in aerobic fitness, muscle strength, and ease of PA are important for maintaining an active lifestyle, a favorable body composition, and high bone density. Traditionally 3 d/wk combined training has been felt to be optimal while recent studies suggest 1 d/wk combined training may create similar adaptations as more frequent training. However, our previous and ongoing studies suggest that 1 d/wk combined aerobic and resistance training (C1) may be insufficient stimulus to induce optimal adaptations and that 3 d/wk combined training (C3) may be too frequent a stimulus for older adults. This study will enable us to compare the effects of C1, 2 d/wk combined training (C2), and C3 on fitness, body composition, ease of PA, PA, and total free-living energy expenditure (TEE). We hypothesize that C2 will result in a larger increase in muscle size, bone density, strength, aerobic capacity, power, ease of PA, PA, and TEE than either C1 or C3. Circulating cytokines and psychological mood states linked to chronic overstress will also be examined. Objectives: We will examine changes in circulating cytokines, mood states, muscle size, bone density, aerobic capacity, strength, power, ease of PA, PA, and TEE following 16 and 32 wks training. Design: We will to evaluate 78 (>60 yrs) Black and White women matched for age, race, and BMI into C1, C2, or C3 groups prior to, after 16, and after 32 wks training. Women will undergo evaluation of metabolic parameters in a General Clinical Research Center. Significance: This study should provide insight into the effects combined training frequency has on improving fitness, ease of PA, and maintenance of a high TEE. Such information is critical to our understanding of ways to improve well being, quality of life, and independence of an aging population.

Study Design

Study Type:
Interventional
Actual Enrollment :
105 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Single (Participant)
Primary Purpose:
Treatment
Official Title:
Frequency of Aerobic/Resistance Training in Older Women
Study Start Date :
Jan 1, 2004
Actual Primary Completion Date :
Mar 1, 2011
Actual Study Completion Date :
Mar 1, 2011

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: Group 1

1 aerobic and 1 resistance training per week

Other: Frequency of Aerobic/Resistance Training - 3 to 3
comparing group results based upon frequency of exercise
Other Names:
  • freqency of aerobic and resistance training

    		•
    Active Comparator: Group 2

    2 aerobic and 2 resistance training each per week

    Other: Frequency of Aerobic/Resistance Training - 3 to 3
    comparing group results based upon frequency of exercise
    Other Names:
  • freqency of aerobic and resistance training

    		•
    Active Comparator: Group 3

    3 aerobic and 3 resistance training per week

    Other: Frequency of Aerobic/Resistance Training - 3 to 3
    comparing group results based upon frequency of exercise
    Other Names:
  • freqency of aerobic and resistance training

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Use a repeated measures analysis to compare differences in TEE and other parameters among the 3 intervention groups across time [over 32 weeks of training]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    60 Years and Older
    Sexes Eligible for Study:
    Female
    Accepts Healthy Volunteers:
    Yes

    Inclusion Criteria:,

    • healthy women over 60 years of age,

    • Caucasian or African-American.

    Exclusion Criteria:

    • smoking,

    • diabetes,

    • osteoporosis,

    • inability to coperform weight bearing exercises, currently performing to much exercise.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 UAB Birmingham Alabama United States 35294

    Sponsors and Collaborators

    • University of Alabama at Birmingham
    • National Institute on Aging (NIA)

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University of Alabama at Birmingham
    ClinicalTrials.gov Identifier:
    NCT01031394
    Other Study ID Numbers:
    • F050820002
    • R01AG027084
    First Posted:
    Dec 14, 2009
    Last Update Posted:
    Oct 27, 2015
    Last Verified:
    Oct 1, 2015
    Keywords provided by University of Alabama at Birmingham
    exercise
    resistance training

    Study Results

    No Results Posted as of Oct 27, 2015