IMAge-8: Effects of Motor Imagery on Motor Learning and Motor Retention in Octogenarian.

Sponsor
Centre Hospitalier Universitaire de Saint Etienne (Other)
Overall Status
Terminated
CT.gov ID
NCT04018196
Collaborator
(none)
84
1
2
26.3
3.2

Study Details

Study Description

Brief Summary

Aging is associated with impairments in cognitive function, particularly motor learning and memorizing, impacting functional capacities. Older adults are still able to learn new skills but at a slower rate, and they forget quickly the new-learned skill because of an alteration in motor memory. Motor imagery, which is a mental simulation of an action without actual execution, has been demonstrated to improve performance in young adults and stabilize performance after a short break in older adults. However, in very old adults (>80 years old) for whom the decline in motor and cognitive functions is greater, it is unknown whether motor imagery training during a short break is still efficient. Previous studies on old adults were performed on upper limb muscles. Because aging differentially affects upper and lower limb muscles, the present study will aim to explore the effects of motor imagery on motor memorizing in both upper and lower limb muscles.

Condition or Disease Intervention/Treatment Phase
  • Other: motor imagery as training manual task
  • Other: motor imagery as training motor task
  • Other: emotionally neutral film as training of manual task
  • Other: emotionally neutral film as training of motor task
N/A

Detailed Description

The primary purpose is to evaluate the effectiveness of motor imagery to improve the performance of very old people (> 80 years) through learning a task of the upper limbs.

Study Design

Study Type:
Interventional
Actual Enrollment :
84 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Other
Official Title:
Effects of Motor Imagery on Motor Learning and Motor Retention in Octogenarian "IMAge-8".
Actual Study Start Date :
Dec 9, 2019
Actual Primary Completion Date :
Feb 14, 2022
Actual Study Completion Date :
Feb 15, 2022

Arms and Interventions

Arm Intervention/Treatment
Experimental: Experimental group

Patient aged over 80 years old will be included. They will have motor imagery training of manual task and motor imagery training of motor task.

Other: motor imagery as training manual task
They will have a motor imagery as training manual task for 30 minutes. They will have 3 tests for performing manual task before training (pretest) and after training (post-test).
Other Names:
  • Nine Hole Peg Test (NHPT)
  • Other: motor imagery as training motor task
    They will have a motor imagery as training motor task for 30 minutes before performing this task. They will have 3 tests for performing motor task before training (pretest) and after training (post-test).
    Other Names:
  • hopscotch
  • Active Comparator: Control group

    Patient aged over 80 years old will be included. They will have emotionally neutral film as training of manual task and emotionally neutral film as training of motor task.

    Other: emotionally neutral film as training of manual task
    They will have to watch an emotionally neutral as training manual task for 30 minutes before performing this task. They will have 3 tests for performing manual task before training (pretest) and after training (post-test).
    Other Names:
  • Nine Hole Peg Test (NHPT)
  • Other: emotionally neutral film as training of motor task
    They will have to watch an emotionally neutral as training motor task for 30 minutes before performing this task. They will have 3 tests for performing motor task before training (pretest) and after training (post-test).
    Other Names:
  • hopscotch
  • Outcome Measures

    Primary Outcome Measures

    1. Performance at the manual task (Nine Hole Peg Test (NHPT)) (s) [Day: 0]

      Comparison of performance at the manual task (Nine Hole Peg Test (NHPT)) results in post-test between experimental and control group. Measured in seconds when performing manual task.

    Secondary Outcome Measures

    1. Performance at the motor task (s) [Day: 7]

      Comparison of performance at the motor task (hopscotch) results pre-test and post-test between experimental and control group. Measured in number of tests.

    2. Learning capacity of manual task (Nine Hole Peg Test (NHPT)) [Day: 0]

      Comparison of manual task (Nine Hole Peg Test (NHPT)) results between pre-test and post-test. Measured in seconds.

    3. Learning capacity of motor task (hopscotch) [Day: 7]

      Comparison of motor task (hopscotch) results between pre-test and post-test. Measured in number of tests.

    4. Test of 6 minutes walking (m) [Day: 0]

      Comparison of test of 6 minutes walking results between experimental and control group. Measured in meters.

    5. Test of Get-up-and-Go (s) [Day: 0]

      Comparison of test of Get-up-and-Go results between experimental and control group. For test of Get-up-and-Go, participants will be asked to stand from a seated position, walk 3 meters at their usual pace, turn around, walk back to the chair, and sit down. Measured in seconds when performing test.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    80 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • Being part of the Proof cohort

    • Signed written consent form

    • Affiliated to social security

    Exclusion Criteria:
    • Pathology or chirurgical intervention causing locomotor disorder

    • Neurological or psychic pathology

    • Use psychotropic drugs

    • Mini-Mental State Examination (MMSE) < 20

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 CHU Saint-Etienne Saint-Étienne France

    Sponsors and Collaborators

    • Centre Hospitalier Universitaire de Saint Etienne

    Investigators

    • Principal Investigator: Léonard FEASSON, MD PhD, CHU SAINT-ETIENNE

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Centre Hospitalier Universitaire de Saint Etienne
    ClinicalTrials.gov Identifier:
    NCT04018196
    Other Study ID Numbers:
    • 18CH128
    • 2018-A02365-50
    First Posted:
    Jul 12, 2019
    Last Update Posted:
    Mar 15, 2022
    Last Verified:
    Mar 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Centre Hospitalier Universitaire de Saint Etienne

    Study Results

    No Results Posted as of Mar 15, 2022