AI-based Frailty Assessment Tool for Patients Undergoing Cardiac Surgery
Study Details
Study Description
Brief Summary
The main purpose of this study is to establish a frailty automatic evaluation index "AI frailty index" based on artificial intelligence multi-modal non-contact monitoring information analysis. At the same time, the study will explore the correlation between ' AI weakness index ' and perioperative and long-term prognosis and quality of life.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
This is a prospective cohort study. Patients who undergoes elective cardiac surgery will be enrolled. We collect frailty scales, clinical information and multi-modal, non-contact monitoring information during hospitalization. One-year follow-up will be done. The non-contact monitoring information are used to predict the frailty scales to establish and validate an AI-based frailty assessment model "AI frailty index". The AI frailty index will be further used to predict perioperative and long-term outcomes.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| AI frailty index establishment group Individuals who undergo elective cardiac surgury |
Other: No intervention
No intervention
|
Outcome Measures
Primary Outcome Measures
- One-dimensional matrix vector composed of five frailty scale results [Before and after surgery, up to 2 weeks]
Consisting of five frailty scales: Edmonton frailty scale, FRAIL frailty scale, Fried frailty scale, Clinical frailty scale, and SPPB
Secondary Outcome Measures
- 30-day adverse events [30 days post operative]
Including death, readmission, stroke, myocardial infarction, renal insufficiency or renal failure, dialysis, atrial fibrillation, peripheral vascular embolism, bleeding events, heart failure
- 1-year adverse events [1 year post operative]
Including death, readmission, stroke, myocardial infarction, renal insufficiency or renal failure, dialysis, atrial fibrillation, peripheral vascular embolism, bleeding events, heart failure
- EQ-5D score [1 year post operative]
The score of EQ-5D questionnaire
- QOR-15 score [1 year post operative]
The score of QOR-15 questionnaire
- Edmonton frailty scale score [1 year post operative]
The Edmonton frailty scale consists of 11 items for a composite score of 0 to 17, and higher scores mean a worse outcome.
- FRAIL frailty scale score [1 year post operative]
The FRAIL frailty scale consists of 5 items, with 3 of 5 required to diagnose frailty.
- Fried frailty scale score [1 year post operative]
The Fried frailty scale consists of 5 items, with 3 of 5 required to diagnose frailty.
- Clinical frailty scale score [1 year post operative]
The Clinical frailty scale is scored 1 to 9 based on a semiquantitative evaluation of the patient's symptoms, mobility, inactivity, exhaustion, and disability for basic activities of daily living and instrumental activities of daily living, and higher scores mean a worse outcome.
- Short Physical Performance Battery scale score [1 year post operative]
The Short Physical Performance Battery scale consists of 3 physical tests, with each scored 0 to 4 for a composite score of 0 to 12, and higher scores mean a better outcome.
- Perioperative adverse events [From surgery to discharge, up to 7 days]
Including all cause death, stroke, renal insufficiency, deep sternal wound infection, and reoperation
- Area under receiver operating curve (AUC) [At the end of follow-up (1 mouth)]
Area under receiver operating curve of algorithm in predicting frailty scales and outcomes
Eligibility Criteria
Criteria
Inclusion Criteria:
- Elective cardiac surgery
Exclusion Criteria:
-
Emergency surgery
-
Age ≤ 18 years
-
The clinical situation is unstable, such as frequent occurrence of coronary ischemia events, unstable heart failure, or acute events leading to severe discomfort symptoms or changes in vital signs
-
Unable to cooperate in completing research data collection due to severe neurological and psychiatric abnormalities or other reasons
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Duration of postoperative ventilation > 48 hours or inability to obtain scale data on the first day after surgery
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Fuwai hospital | Beijing | Beijing | China | 100032 |
Sponsors and Collaborators
- China National Center for Cardiovascular Diseases
Investigators
- Principal Investigator: Shen Lin, MD, PhD, Fuwai Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2023-GSP-RC-10