Alcohol and Other Psychoactive Substances in Road Traffic - a Case-control Study

Sponsor

Finnish Institute for Health and Welfare (Other)

Overall Status

Unknown status

CT.gov ID

NCT00570518

Collaborator

Hospital District of Helsinki and Uusimaa (Other), European Commission (Other)

4,500

Enrollment

Location

Duration (Months)

91.9

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The main purpose of the study is to determine the accident risk when driving under the influence of psychoactive substances, including alcohol (DUI). Other aims are to find out the prevalence of psychoactive substances in road traffic and to obtain information on the role of these substances in road traffic accident causations.

For the purposes of the study, drivers of motorised vehicles are randomly stopped and interviewed and breath alcohol is recorded. Also, an oral fluid sample is taken and psychoactive substances are investigated in the laboratory. For cases, drivers injured in traffic accidents are asked to participate to the study. A whole blood sample and, if possible, an oral fluid sample is taken and psychoactive substances are determined in the laboratory. Also, people diseased in road traffic accident are included in the study. The information required for these subjects are taken from a register database.

The study is part of an EU-project DRUID. Altogether 13 European countries take part to the study.

Condition or Disease	Intervention/Treatment	Phase
Prevalence of Psychoactive Substances in Road Traffic Psychoactive Substances in Accident Involved Drivers Relative Risk Estimation of Accident Involvement for Impaired Drivers

Study Design

Study Type:

Observational

Anticipated Enrollment :

4500 participants

Observational Model:

Case-Control

Official Title:

DRUID Work Package 2 - Epidemiology

Study Start Date :

Sep 1, 2007

Anticipated Study Completion Date :

Oct 1, 2011

Arms and Interventions

Arm	Intervention/Treatment
1 randomly stopped drivers of motorised vehicles and bicycles
2 drivers of motorised vehicles and bicycles injured or killed in road traffic accidents

Outcome Measures

Primary Outcome Measures

relative risk estimation of accident involvement for drivers impaired by psychoactive substances [three years]

Secondary Outcome Measures

prevalence of psychoactive substances in the general driving population [three years]
prevalence of psychoactive substances among accident involved drivers [three years]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

18 years or older
driver of a motorised vehicle or bicycle
is willing to participate to the study (not applicable to the diseased drivers; information obtained from a register database)

Exclusion Criteria:

17 or younger
not the driver of a motorised vehicle or bicycle
does not want to participate (not applicable to the diseased drivers; information obtained from a register database)