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Does Mixing Alcoholic Drinks Make Hangover Worse?

Sponsor
Zealand University Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT03506516
Collaborator
(none)
35
Enrollment
2
Arms
20.4
Actual Duration (Months)

Study Details

Study Description

Brief Summary

Does mixing alcohol make hangover worse?

Condition or Disease Intervention/Treatment Phase
  • Dietary Supplement: Mixing alcohol
  • Dietary Supplement: Single type alcohol
 N/A

Detailed Description

Hangover is the most commonly occurring morbidity associated with heavy drinking.

Our aim was to test the hypothesis that mixing alcoholic drinks as compared to drinking one type of alcohol only (beer, wine or spirits) associate with a higher alcohol intake and worse hangover.

Study Design

Study Type:
Interventional
Actual Enrollment :
35 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose:
Health Services Research
Official Title:
Does Mixing Alcoholic Drinks Make Hangover Worse? A Randomized Controlled Trial in a Naturalistic Setting
Actual Study Start Date :
May 20, 2016
Actual Primary Completion Date :
May 30, 2016
Actual Study Completion Date :
Jan 31, 2018

Arms and Interventions

Arm Intervention/Treatment
Experimental: single type

Restricted to drinking only one type of alcohol

Dietary Supplement: Single type alcohol
Alcoholic beverages, different types
Other Names:
  • Ethanol

    		•
    Active Comparator: mixed type

    Drinking and mixing different types of alcohols freely

    Dietary Supplement: Mixing alcohol
    Alcoholic beverages, different types
    Other Names:
  • Ethanol

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Acute Hangover Severity Scale (AHSS) [Baseline]

      AHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.

    Secondary Outcome Measures

    1. Number of drinks [Baseline]

      Total number of drinks defined as 12 g of alcohol consumed during evening

    2. Acute Hangover Severity Scale (AHSS) 2 [after 4 hours]

      AHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.

    3. Acute Hangover Severity Scale (AHSS) 3 [after 8 hours]

      AHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • written and oral consent

    • minimum 18 years old

    • participating in Danish Health Research Retreat in Turkey 2016

    • will consume alcoholic beverages

    Exclusion Criteria:

    • underage

    • will not consume alcoholic beverages

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Zealand University Hospital

    Investigators

    • Principal Investigator: Ole G Christiansen, MD, Zealand University Hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Zealand University Hospital
    ClinicalTrials.gov Identifier:
    NCT03506516
    Other Study ID Numbers:
    • VEK16028829
    First Posted:
    Apr 24, 2018
    Last Update Posted:
    Apr 24, 2018
    Last Verified:
    Apr 1, 2018
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Zealand University Hospital
    alcohol, hangover
    Additional relevant MeSH terms:
    Alcohol-Related Disorders
    Ethanol

    Study Results

    No Results Posted as of Apr 24, 2018