Effects of Dual-Task Training In Individuals With Alzheimer

Sponsor
Ege University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05765552
Collaborator
(none)
34
1
2
12
2.8

Study Details

Study Description

Brief Summary

The purpose of this study is to investigate the effects of dual-task training on balance, fear of falling, cognitive functions, dual-task performance, depression and quality of life in individuals with Alzheimer.

Condition or Disease Intervention/Treatment Phase
  • Other: Dual-Task Training
  • Other: Control Group
N/A

Detailed Description

Eligible participants will be randomized to control or dual-task training group.Control group will receive conventional therapy generally consisted of lower and upper range of motion exercises for 30 minutes 2 times a week for 8 weeks.Dual-task training group will receive exercises involving motor-cognitive dual-task exercises for 30 minutes 2 times a week for 8 weeks.Each participant will be assessed before and after the 8 weeks of treatment.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
34 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Effects Of Dual-Task Training On Balance, Fear Of Falling,Cognitive Functions, Dual-Task Performance, Depression And Quality Of Life In Individuals With Alzheimer
Anticipated Study Start Date :
Apr 15, 2023
Anticipated Primary Completion Date :
Dec 15, 2023
Anticipated Study Completion Date :
Apr 15, 2024

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: Control Group

Participants in control group will receive an exercise program consisted of upper and lower range of motion exercises.The exercises will be started as 8-10 repetitions and 1 set and the number of sets will be increased according to the progression of the patient. Exercises will be applied for 8 weeks, 2 days a week, each session will last for 30 minutes.

Other: Control Group
Upper and lower extremity range of motion exercises will be applied for 8-10 repetitions for 1 set 2 times a week for 8 weeks.

Experimental: Dual-Task Training Group

Participants in the dual-task training group will receive exercises involving both motor and cognitive functions.Dual-task training sessions will begin with 10 minutes of stretching and proceed with 20 minutes of motor-cognitive dual-task exercises (counting backwards from 30 on double stance, naming the months and singing when standing on soft surfaces, finding words that starts with a given letter etc.) and sessions will end with 10 minutes of cooling.Exercises will be applied for 8 weeks 2 days a week each session will last for 30 minutes.

Other: Dual-Task Training
Motor-cognitive dual-task exercises will be applied for 2 days a week for 8 weeks.Sessions will last for 30 minutes.

Outcome Measures

Primary Outcome Measures

  1. Timed Up And Go(TUG) [eight weeks]

    It is a frequently used test that evaluates functional mobility and dynamic balance. At the beginning of the test, individuals sit in a chair. A distance of 3 m is set in front of the patient. With the start command, the patient gets up from his seat and walks 3 m, turns around and walks back and sits. With the start command, the time until the moment of sitting on the chair is recorded in seconds.Shorter duration indicates better functional mobility.

  2. 5 Times Sit To Stand Test(5XSST) [eight weeks]

    5XSST evaluates lower extremity functional strength, transitional movements, balance and fall risk. The time it takes for the participant to sit and get up from a chair 5 times is recorded in seconds. Interpretations are made about balance and fall risk by comparing the norm times for age with the time the individual completes the test.

  3. Cognitive Reserve Index Questionaire(CRIq) [eight weeks]

    CRIq assesses an individual's cognitive reserve through compiling information about their entire adult life. If the participant has a suspected or confirmed cognitive weakness, the questionnaire must be answered by a family member or caregiver. The total score is obtained by recording the frequency of the individual's educational life, work and leisure activities in years. According to the score, the participant's cognitive reserve is interpreted as low, low - medium, medium, medium - high or high

  4. Quality of Life in Alzheimer's Disease(QOL-AD) [eight weeks]

    There are two versions of the scale: patient and family member/caregiver. In order to maximize construct validity, the scale is filled in independently by both patients and caregivers. It consists of questions asked about different aspects of life in order to determine the quality of life of the person. For each question, they are asked to choose the most appropriate one from the Poor, Fair, Good or Excellent answers.Higher scores indicate better quality of life.

  5. Geriatric Depression Scale(GDS) [eight weeks]

    The scale consists of 30 questions questioning how the participant felt in the past week. The person is asked to give the appropriate Yes(0) or No(1) answer to each question.Scores higher than 5 indicate depression.

Secondary Outcome Measures

  1. Dual-Task Questionnaire(DTQ) [eight weeks]

    The Dual Task Questionnaire assesses the frequency of difficulties experienced by individuals with neurological injury or disease during activities of daily living that involve dual tasks. DTQ is scored between 0-40. Higher scores indicate more frequent dual-task difficulties.

  2. Modified Falling Efficacy Scale(MFES) [eight weeks]

    The scale consists of 14 items. On a scale of 0 to 10 (on the scale), the participant asked how safe they feel doing each of these activities without falling, with 0 being "not safe/not sure", 5 "quite safe/quite confident", and 10 "completely safe/ are asked to rate it in terms of being completely sure.

  3. Mini Mental Test(MMT) [eight weeks]

    Scoring is made between 0-30 on the scale in which the sub-headings of orientation, recording memory, attention and calculation, recall, language are evaluated.Lesser scores indicate worse cognitive function.

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • having been diagnosed with mild or moderate Alzheimer's disease

  • able to walk with or without assistance

  • having sufficient visual and auditory ability to perform the cognitive tests

  • being fit to perform physical exercises

  • being able to participate in proposed interventions and assessments

Exclusion Criteria:
  • having a neurological disorder other than Alzheimer

  • having any musculoskeletal problems that can affect balance

  • having any contraindication to exercise

  • functional limitation or sensory impairment that may affect performance

  • major depression

Contacts and Locations

Locations

Site City State Country Postal Code
1 Karsiyaka Municipality Day Living Center İzmir Karsıyaka Turkey 35580

Sponsors and Collaborators

  • Ege University

Investigators

  • Study Chair: Sevnaz ŞAHIN, PhD, Ege University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Mehmet Ozkeskin, Asisstant Professor, Ege University
ClinicalTrials.gov Identifier:
NCT05765552
Other Study ID Numbers:
  • MOzkeskin874
First Posted:
Mar 13, 2023
Last Update Posted:
Mar 13, 2023
Last Verified:
Mar 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Mehmet Ozkeskin, Asisstant Professor, Ege University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Mar 13, 2023