Effect of 3D Movie Viewing on Stereopsis in Strabismus and / or Anisometropic Amblyops
Study Details
Study Description
Brief Summary
This study evaluates the effect of 3D movie viewing on stereopsis recovery in anisometropic and / or strabismus amblyopia and the satisfaction with the intervention.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
Amblyopia is a visual neurodevelopmental disorder associated, more frequently, with the presence of strabismus and anisometropia. It is clinically most important visual condition in childhood because, apart from refractive error, it is the most frequent cause of vision loss in children. It is a reversible condition that affects up to 5% of the population, and that is the result of an abnormal visual experience during the most sensitive period of visual development. Although amblyopia is expressed in the clinical practice as a reduction in visual acuity, it is also characterized by an altered stereoscopy. Generally, treatments for amblyopia focus on the recovery of visual acuity, and there are no treatments that focus mainly on the recovery of the altered stereopsis, so present and with an important functional impact.
The aim of this study reviewing, analyzing and, if applicable, updating the current treatment model for amblyopia. On the one hand, to evaluate the effectiveness of viewing a 3D movie in the improvement of stereoacuity and the deviation, as well as visual acuity and sensitivity to contrast. Also, the correlation between them. On the other hand, to assess quantitatively the degree of satisfaction and acceptance of the participants and their families towards the intervention.
A quasi-experimental study will be performed, without a control group, pre- and post- intervention in which subjects with refractive and / or strabismus amblyopia, that have been subjected to traditional treatment for amblyopia, will be selected. Variables of stereopsis, latent or manifest deviation, visual acuity and sensitivity to the contrast will evaluate previously and after the intervention.
The sample will include subjects between 5 to 12 years old with a diagnosis of refractive and / or strabismic amblyopia.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: 3D movie 3D movie viewing |
Other: 3D movie viewing
3D movie viewing
|
Outcome Measures
Primary Outcome Measures
- Change from baseline Stereopsis (ST with StereoTAB) at 2 weeks and 3 months studying the effect of viewing a 3D movie in the visual function. [Baseline, 2 weeks and 3 months]
Stereopsis (ST in logMAR) will be evaluated by a Multiple Random Points test through an Ipad. The app is StereoTAB and uses anaglyphic glasses. The measures will be performed at 50 cm.
- Change from baseline Stereopsis (ST with Randot Dot Test) at 2 weeks and 3 months studying the effect of viewing a 3D movie in the visual function. [Baseline, 2 weeks and 3 months]
Stereopsis (ST in logMAR) will be evaluated by a Randot Dot Test. The measures will be performed at 40 cm.
- Change from baseline latent or manifest deviation at 2 weeks and 3 months studying the effect of viewing a 3D movie in the visual function. [Baseline, 2 weeks and 3 months]
Latent o manifest deviation will be evaluated in the two distances (40 cm and 6 m) and will be measured by prisms.
Secondary Outcome Measures
- Satisfaction assessed by an ordinal questionnaire designed based on the Treatment Satisfaction Questionnaire for Medication (TSQM). [2 weeks]
Satisfaction assessed by an ordinal questionnaire (1 to 5, as 1 the lowest satisfaction and 5 the highest satisfaction), based on the TSQM (Treatment Satisfaction Questionnaire for Medication) version 1.4 to provide data regarding the degree of satisfaction and sensation of parents and children in relation to treatment.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Diagnosis of refractive and / or strabismus amblyopia at some point in life
-
History of amblyopia treatment completed at least 6 months before the intervention
-
Deviation angle equal to or less than 10 Dp
-
Absence of associated ophthalmological pathology.
Exclusion Criteria:
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Ongoing amblyopia treatment;
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Non-comitant and/or large constant strabismus (>10 prism diopters)
-
Any ocular pathological condition or nystagmus.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Laura Asensio Jurado | Barcelona | Spain |
Sponsors and Collaborators
- Universitat Politècnica de Catalunya
- Hospital Mutua de Terrassa
Investigators
- Principal Investigator: Laura Asensio Jurado, MsC, Universitat Politècnica de Catalunya
- Study Director: Marc Argilés Sans, PhD, Universitat Politècnica de Catalunya
- Study Director: Lluïsa Quevedo i Junyent, PhD, Universitat Politècnica de Catalunya
Study Documents (Full-Text)
None provided.More Information
Publications
- Birch EE, Jost RM, De La Cruz A, Kelly KR, Beauchamp CL, Dao L, Stager D Jr, Leffler JN. Binocular amblyopia treatment with contrast-rebalanced movies. J AAPOS. 2019 Jun;23(3):160.e1-160.e5. doi: 10.1016/j.jaapos.2019.02.007. Epub 2019 May 16.
- Bossi M, Tailor VK, Anderson EJ, Bex PJ, Greenwood JA, Dahlmann-Noor A, Dakin SC. Binocular Therapy for Childhood Amblyopia Improves Vision Without Breaking Interocular Suppression. Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):3031-3043. doi: 10.1167/iovs.16-20913.
- Bridgeman B. Restoring adult stereopsis: a vision researcher's personal experience. Optom Vis Sci. 2014 Jun;91(6):e135-9. doi: 10.1097/OPX.0000000000000272.
- Levi DM, Knill DC, Bavelier D. Stereopsis and amblyopia: A mini-review. Vision Res. 2015 Sep;114:17-30. doi: 10.1016/j.visres.2015.01.002. Epub 2015 Jan 29. Review.
- Li RW, Tran KD, Bui JK, Antonucci MM, Ngo CV, Levi DM. Improving Adult Amblyopic Vision with Stereoscopic 3-Dimensional Video Games. Ophthalmology. 2018 Oct;125(10):1660-1662. doi: 10.1016/j.ophtha.2018.04.025. Epub 2018 May 18.
- PhDLAJE2