Aminophylline Prophylaxis For Postdural Puncture Headache
Sponsor
Diskapi Yildirim Beyazit Education and Research Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT02150304
Collaborator
(none)
100
1
5
20.2
Study Details
Study Description
Brief Summary
postdural puncture headache is a rare but serious complication of spinal anesthesia. many drugs were studied in prevention or treatment of that complication. However, there are limited numbers of trials about intravenous aminophylline for prevention. because of that we retrospectively aimed to investigate the effectiveness of aminophylline for postdural puncture headache in cesarean section.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
|
Detailed Description
retrospective trial about the effect of intravenous aminophylline for prevention of PDPH after caserean section with spinal anesthesia
Study Design
Study Type:
Observational
Actual Enrollment
:
100 participants
Observational Model:
Case-Control
Time Perspective:
Retrospective
Official Title:
Phase IV Study of Intravenous Aminophylline During Spinal Anesthesia
Study Start Date
:
Jan 1, 2014
Actual Primary Completion Date
:
Jun 1, 2014
Actual Study Completion Date
:
Jun 1, 2014
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| intravenous aminophylline intravenous aminophylline use during spinal anesthesia |
|
| no intravenous aminophylline no use of intravenous aminophylline during spinal anesthesia |
Outcome Measures
Primary Outcome Measures
- postdural puncture headache [postoperative 2 weeks]
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
to 45 Years
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- patients aolder than 18 years old
Exclusion Criteria:
- conversion to general anesthesia
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Dışkapı Yıldırım Beyazıt Education and Research Hospital | Ankara | Turkey | 06110 |
Sponsors and Collaborators
- Diskapi Yildirim Beyazit Education and Research Hospital
Investigators
- Principal Investigator: ibrahim öztürk, M.D., dışkapı yıldırım beyazıt education and research hospital
Study Documents (Full-Text)
None provided.More Information
Publications
- Basurto Ona X, Uriona Tuma SM, Martínez García L, Solà I, Bonfill Cosp X. Drug therapy for preventing post-dural puncture headache. Cochrane Database Syst Rev. 2013 Feb 28;(2):CD001792. doi: 10.1002/14651858.CD001792.pub3. Review.
- Naghibi K, Hamidi M. Prophylactic administration of aminophylline plus dexamethasone reduces post-dural puncture headache better than using either drug alone in patients undergoing lower extremity surgery. Adv Biomed Res. 2014 Jan 9;3:5. doi: 10.4103/2277-9175.124631. eCollection 2014.
Responsible Party:
İBRAHİM ÖZTÜRK,
doctor,
Diskapi Yildirim Beyazit Education and Research Hospital
ClinicalTrials.gov Identifier:
NCT02150304
Other Study ID Numbers:
- PDPHAMINOPHYLLINE
First Posted:
May 29, 2014
Last Update Posted:
Aug 5, 2015
Last Verified:
Aug 1, 2015