Anaesthetic Management of Women With Heart Disease For Labor and Delivery

Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT00403871
Collaborator
(none)
700
2
31
350
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Study Details

Study Description

Brief Summary

Heart disease among pregnant women is increasing in incidence. The cardiovascular changes associated with pregnancy may be particularly hazardous for both mother and fetus in a subset of these patients. The period of greatest risk is peripartum while these patients are under the care of the obstetrician and anesthesiologist. We will evaluate the anesthetic management of all women with heart disease whose pregnancies were followed at the University Health Network and/or Mount Sinai Hospital between 1986 and 2001.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Heart disease among pregnant women is increasing in incidence. The cardiovascular changes associated with pregnancy may be particularly hazardous for both mother and fetus in a subset of these patients. The period of greatest risk is peripartum while these patients are under the care of the obstetrician and anesthesiologist. Exposing a compromised patient to general anesthesia is further complicated by the cardiovascular stress response to intubation and surgery, the cardiorespiratory implications of mechanical ventilation, the cardiac depression and vasodilation from general anesthetics, residual post-operative respiratory depression from general anesthetics and narcotics and the stress of weaning from mechanical ventilation and post-operative pain.

    In the Adult Congenital Heart Program, obstetric patients are followed the by a specialized team of cardiologists, obstetricians and anesthesiologists who also follow all pregnant women referred with acquired cardiac disease. From this referral practice approximately 100 patients per year are now followed during their pregnancy and delivery. In conjunction with the ongoing system we intend to identify all parturients who delivered at the University Health Network (Toronto General Hospital) or Mount Sinai Hospital between the years 1986 and 2001. We will evaluate the anesthetic management of all women with heart disease whose pregnancies were followed at the University Health Network and/or Mount Sinai Hospital between 1986 and 2001.

    Study Design

    Study Type:
    Observational
    Observational Model:
    Defined Population
    Time Perspective:
    Other
    Official Title:
    Anaesthetic Management of Women With Heart Disease For Labor and Delivery
    Study Start Date :
    Nov 1, 2002
    Study Completion Date :
    Jun 1, 2005

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      N/A and Older
      Sexes Eligible for Study:
      Female
      Accepts Healthy Volunteers:
      No
      Inclusion Criteria:
      • Pregnant women with congenital or acquired heart disease

      • Pregnant women with arrhythmias are also included providing they had had symptomatic tachyarrhythmias or bradyarrhythmias requiring treatment

      Exclusion Criteria:
      • Women with isolated mitral valve prolapse including those with mild to moderated mitral regurgitation

      • Women referred for termination of pregnancy

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 Mount Sinai Hospital Toronto Ontario Canada M5G 1X5
      2 Univeristy Health Network Toronto Ontario Canada M5G 1Z5

      Sponsors and Collaborators

      • Samuel Lunenfeld Research Institute, Mount Sinai Hospital

      Investigators

      • Principal Investigator: Eric Goldszmidt, MD, Mount Sinai Hosiptal

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT00403871
      Other Study ID Numbers:
      • 06-05
      • 02-0211-E
      First Posted:
      Nov 27, 2006
      Last Update Posted:
      Mar 2, 2007
      Last Verified:
      Feb 1, 2007
      Keywords provided by , ,
      Additional relevant MeSH terms:

      Study Results

      No Results Posted as of Mar 2, 2007