Effect of Pumpkin Seed Oil on Hair Growth in Men With Androgenetic Alopecia

• Sponsor: Dream Plus (Industry)
• Overall Status: Completed
• CT.gov ID: NCT01852487
• Collaborator: (none)
• Enrollment: 80
• Location: 1
• Arms: 2
• Duration (Months): 10
• Patients Per Site Per Month: 8

Study Details

Study Description

Brief Summary

Androgenic alopecia is the most common cause of hair loss in men. Finasteride and minoxidil are available in treatment of androgenetic alopecia, although the former causes decreased libido or ejaculate volume, erectile dysfunction, the latter causes scaling, itching of the scalp. Recently, Pulpkin Seed Oil shows some improved clinical efficacy on scalp hair growth in men with androgenetic alopecia, but there is no evidence to support this.

The investigators conducted a randomized, double-blind, placebo-controlled efficacy and tolerability trial of Pumpkin seed oil (400mg/day)therapy in male patients with androgenetic alopecia.

Condition or Disease	Intervention/Treatment	Phase
Androgenic Alopecia	Dietary Supplement: 400mg /day during 6 months	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 80 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
• Primary Purpose: Treatment
• Study Start Date: Feb 1, 2012
• Actual Primary Completion Date: Dec 1, 2012
• Actual Study Completion Date: Dec 1, 2012

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: Pumpkin Seed Oil 400mg/ day during 6 months	Dietary Supplement: 400mg /day during 6 months
Placebo Comparator: sweet potato starch 400mg/day during 6months

Outcome Measures

Primary Outcome Measures

1. investigator assessment score using photographs of scalp hair [at weeks 12 and 24]

Secondary Outcome Measures

1. patient self-assessment scores [at weeks 12 and 24]

Other Outcome Measures

1. hair analysis using phototrichogram [at weeks 12 and 24]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 65 Years
• Sexes Eligible for Study: Male
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• 18 to 65 years of age

• Androgenetic alopecia of Norwood-Hamilton scale grade II-V

Exclusion Criteria:

• Severe medical problems including renal problems, prostate diseases, diabetes mellitus o

• Patients who took any medicine which can affect the hair growth in recent 3 months.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Pusan National University Yangsan Hospital	Yangsan	Gyeongsangnam-do	Korea, Republic of	626-770

Sponsors and Collaborators

• Dream Plus

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Young Hye Cho, Professor, Pusan National University Yangsan Hospital
• ClinicalTrials.gov Identifier: NCT01852487
• Other Study ID Numbers: Pumpkin0912
• First Posted: May 13, 2013
• Last Update Posted: May 13, 2013
• Last Verified: May 1, 2013

• Keywords provided by Young Hye Cho, Professor, Pusan National University Yangsan Hospital: Pumpkin seed oil; Hair growth; Men
• Additional relevant MeSH terms: Alopecia; Alopecia Areata

Study Results

No Results Posted as of May 13, 2013