Clincosm LogoSign in Get a demo

Iron Deficiency Anemia in Twin Pregnancies

Sponsor
Shengjing Hospital (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT04975074
Collaborator
(none)
1,000
Enrollment
2
Arms
11.5
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

All pregnant women with twin pregnancies were given oral iron according to the current recommended dose. Blood routine and ferritin were monitored during pregnancy to understand the therapeutic effect of oral iron on iron deficiency anemia and iron deficiency in pregnant women with twin pregnancies

Condition or Disease Intervention/Treatment Phase
Phase 4

Detailed Description

All pregnant women with twin pregnancies were given oral iron according to the current recommended dose. Blood routine and ferritin were monitored every 2-4 weeks during pregnancy to understand the therapeutic effect of oral iron on iron deficiency anemia and iron deficiency in pregnant women with twin pregnancies.After delivery, we will test the neonatal ferritin and hemoglobin status. Our aim was to investigate the effects of iron supplementation during twin pregnancy on maternal and neonatal ferritin and anemia.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
1000 participants
Allocation:
Non-Randomized
Intervention Model:
Sequential Assignment
Masking:
None (Open Label)
Primary Purpose:
Prevention
Official Title:
Prospective Study of Iron Deficiency Anemia in Twin Pregnancy
Anticipated Study Start Date :
Jul 15, 2021
Anticipated Primary Completion Date :
Dec 1, 2021
Anticipated Study Completion Date :
Jul 1, 2022

Arms and Interventions

Arm Intervention/Treatment
Experimental: Anemia Correction Group

Continue to take the current medication orally at the current dose

Drug: Iron
One of each type of iron was taken orally according to the instructions and followed every two weeks
Other Names:
  • ferrous sulfate
  • polyferose
  • ferrous succinate
  • Chinese medicine filling iron agent

    		•
    Experimental: Anemia uncorrected group

    Continue to take the current medication orally at the current dose

    Drug: Iron
    One of each type of iron was taken orally according to the instructions and followed every two weeks
    Other Names:
  • ferrous sulfate
  • polyferose
  • ferrous succinate
  • Chinese medicine filling iron agent

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Routine blood [2-4 weeks after antenatal care]

      Routine blood and serum ferritin（ng/ml）were checked 2-4 weeks

    Secondary Outcome Measures

    1. serum ferritin [2-4 weeks after antenatal care]

      routine blood and serum ferritin（ng/ml）were checked 2-4 weeks

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    16 Years to 50 Years
    Sexes Eligible for Study:
    Female
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Chinese

    • Pregnant women with twin pregnancies

    Exclusion Criteria:

    • Single pregnancy

    • Types of anemia other than iron deficiency anemia

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Shengjing Hospital

    Investigators

    • Study Chair: Caixia Liu, Shengjing Hospital of CMU

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Caixia Liu, Clinical Professor, Shengjing Hospital
    ClinicalTrials.gov Identifier:
    NCT04975074
    Other Study ID Numbers:
    • IDA in TP
    First Posted:
    Jul 23, 2021
    Last Update Posted:
    Jul 23, 2021
    Last Verified:
    Jul 1, 2021
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Anemia
    Anemia, Iron-Deficiency
    Iron
    Ferrous succinate

    Study Results

    No Results Posted as of Jul 23, 2021