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Impact of Dried Moringa Oleifera Leaves in Enhancing Hemoglobin Status

Sponsor
Kinnaird College for Women (Other)
Overall Status
Completed
CT.gov ID
NCT03514472
Collaborator
(none)
34
Enrollment
2
Arms
14.9
Actual Duration (Months)

Study Details

Study Description

Brief Summary

This research project is aimed at combating the nutritional deficiencies (Iron deficiency anemia) of reproductive aged females belonging to the underprivileged group of the society. Since anemia is one of the causes of still child-birth, preterm and low birth weight babies causing cognitive disabilities during the later years of life, So, it needs to be treated on priority bases.

Condition or Disease Intervention/Treatment Phase
  • Dietary Supplement: Dried Moringa oleifera leaves
 N/A

Detailed Description

Mal-nutrition is a significant problem in the developing world, with serious consequences for human health and socio-economic development. It is estimated that over 43% women of reproductive age suffer from anemia. In Pakistan, about 35% non-pregnant and 51% pregnant women are suffering from anemia. Prevention and control against anemia rely on iron supplementation and food fortification on large scale. Both these methods are not affordable and feasible for poor people. Previous studies have shown that about 97% females do not meet their iron requirements. The possible reason to this can be iron losses from body including menstruation. To overcome these problems, culturally accepted, inexpensive and modified recipes were used to supply iron with addition of Moringa oleifera leaves (rich and cheap source of iron). In the study 34 of ages between 13-30 years were selected (excluding pregnant and lactating women) and were intervened with value added supplement " Moringa oleifera" for a period of three months. These recipes were made part of the diet by giving a dose of three meals per day on regular basis. Each recipe contained about 15 g of Dried Moringa powder. After the intervention, out of total 34, 3 females achieved normal Hb level of 12 g/dl. Overall, 94% cases of the study showed improvement of 1.8 g/dl (on average) in Hb level after intervention. There was a significant increase in blood Hb level (p<0.000) and both the var5iables were strongly and positively correlated (0.928). Variables of age and levels of education were weakly but significantly related to each other (p<0.001) in improving Hb after intervention.

Females with higher levels of education showed better response towards intervention.

After intervention with Moringa oleifera, an average increase of 1.5 g/dl in Hb was observed in the entire population whereas, members of Group B (ages above 18) showed more increase of 14.96% in their Hb level as compared to members of Group A (ages below 18) showing an increase of 12.96% in Hb level.

Study Design

Study Type:
Interventional
Actual Enrollment :
34 participants
Allocation:
Non-Randomized
Intervention Model:
Single Group Assignment
Intervention Model Description:
In the study 34 of ages between 13-30 years divided into 2 age groups (below and above 18) were selected (excluding pregnant and lactating women) and were intervened with value added supplement " Moringa oleifera" for a period of three months.In the study 34 of ages between 13-30 years divided into 2 age groups (below and above 18) were selected (excluding pregnant and lactating women) and were intervened with value added supplement " Moringa oleifera" for a period of three months.
Masking:
None (Open Label)
Primary Purpose:
Supportive Care
Official Title:
Impact of Dried Moringa Oleifera Leaves as Value Added Supplement in Enhancing Hemoglobin Status of Reproductive Aged Females of Low Socio-economic Group
Actual Study Start Date :
Jan 1, 2013
Actual Primary Completion Date :
Dec 1, 2013
Actual Study Completion Date :
Apr 1, 2014

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: Group A (Below 18 years)

Dried Moringa oleifera leaves (15g/recipe)

Dietary Supplement: Dried Moringa oleifera leaves
Active Comparator: Group B (Above 18)

Dried Moringa oleifera leaves (15g/recipe)

Dietary Supplement: Dried Moringa oleifera leaves

Outcome Measures

Primary Outcome Measures

  1. Improvement in Hemoglobin status [3 months]

    Comparison of Hb levels pre and post intervention

Secondary Outcome Measures

  1. Changes in BMI [5 months]

    Changes in BMI after improvement in Hb status

Eligibility Criteria

Criteria

Ages Eligible for Study:
13 Years to 30 Years
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Reproductive aged females (13-30 years)
Exclusion Criteria:
  • pregnant and Lactating women

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Kinnaird College for Women

Investigators

  • Principal Investigator: Madeeha Munir, M.Phil, Kinnaird College for Women

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Madeeha Munir, Former Lecturer Minhaj University, Kinnaird College for Women
ClinicalTrials.gov Identifier:
NCT03514472
Other Study ID Numbers:
  • MMunir
First Posted:
May 2, 2018
Last Update Posted:
May 2, 2018
Last Verified:
May 1, 2018
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Madeeha Munir, Former Lecturer Minhaj University, Kinnaird College for Women
Hb, Anemia,
Additional relevant MeSH terms:
Anemia, Iron-Deficiency

Study Results

No Results Posted as of May 2, 2018