Erector Spinae Plane Block Versus Quadratus Lumborum Block For Postoperative Analgesia After Abdominal Hysterectomy

• Sponsor: Ain Shams University (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT05541588
• Collaborator: (none)
• Enrollment: 64
• Location: 1
• Arms: 2
• Anticipated Duration (Months): 5.8
• Patients Per Site Per Month: 10.9

Study Details

Study Description

Brief Summary

The aim of this study is to compare the analgesic efficacy of erector spinae plane block and quadratus lumborum block after abdominal hysterectomy surgery and postoperative opioid consumption.

Condition or Disease	Intervention/Treatment	Phase
Anesthesia	Procedure: peripheral nerve block	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 64 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Double (Participant, Outcomes Assessor)
• Primary Purpose: Supportive Care
• Official Title: Erector Spinae Plane Block Versus Quadratus Lumborum Block For Postoperative Analgesia After Abdominal Hysterectomy; A Randomized Comparative Study
• Actual Study Start Date: Jul 7, 2022
• Anticipated Primary Completion Date: Jan 1, 2023
• Anticipated Study Completion Date: Jan 1, 2023

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: ESPB Erector Spinae Plane Block group	Procedure: peripheral nerve block; ultrasound guided nerve block
Active Comparator: QLB Quadratus Lumborum Block group	Procedure: peripheral nerve block; ultrasound guided nerve block

Outcome Measures

Primary Outcome Measures

1. Post-operative pain [24 hours]

   Post-operative pain severity assessed by visual analog scale (VAS) (range from 0-10., 0 no pain, 10 worst pain ).

Secondary Outcome Measures

1. Cumulative post-operative opioid consumption [24 hours]

   opioid consumption

2. The onset of 1st analgesic request [24 hours]

   time needed for 1st request of rescue analgesia

Other Outcome Measures

1. Incidence of complications [24 hours]

   postoperative nausea and vomiting(PONV), hematoma, local anaesthetic toxicity (LAT)

Eligibility Criteria

Criteria

• Ages Eligible for Study: 40 Years to 80 Years
• Sexes Eligible for Study: Female
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Patients with American Society of Anesthesiologists (ASA) physical status 1-3.

• scheduled for abdominal hysterectomy surgery.

Exclusion Criteria:

• History of allergy to the medications used in the study.

• Contraindication to regional anesthesia as coagulopathy, local infection.

• Severe hepatic impairment (child C).

• Sever Renal dysfunction (creatinine clearance < 30).

• Psychiatric or mental disorder affecting patient ability to interpret VAS score.

• Body mass index (BMI) ≥ 40 or ≤ 18 kg/m2.

• ASA IV.

• Patient refusal.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Ain Shams univerisity	Cairo		Egypt

Sponsors and Collaborators

• Ain Shams University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Khaled Abdou, clinical assistant professor -Ain Shams University, Ain Shams University
• ClinicalTrials.gov Identifier: NCT05541588
• Other Study ID Numbers: ASUKH1
• First Posted: Sep 15, 2022
• Last Update Posted: Sep 19, 2022
• Last Verified: Sep 1, 2022

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Study Results

No Results Posted as of Sep 19, 2022