The Effects of Anger and Joy Expressions on Approach and Avoidance Behaviors in Healthy Volunteers

Sponsor

University Hospital, Montpellier (Other)

Overall Status

Recruiting

CT.gov ID

NCT04899609

Collaborator

(none)

Enrollment

Location

Anticipated Duration (Months)

2.1

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Social interactions are part of our daily lives. Communicating with others is a recurring choice which is based on emotional cues, such as facial expression. Our action must be adapted to the emotional state of our interlocutor, otherwise the investigators will have poor quality interactions An emotional stimulus would cause a conditioned response (innate reaction). Thus, the presence of an angry person would automatically trigger flight behavior. More recently, however, it has been envisioned that this same avoidance behavior could be the result of a goal-directed behvior. In this case, the avoidance behavior would be the result of an evaluation of the consequences of the selected action. These goal-directed behaviors are guided by a mental representation of consequences The project aims to study behavioral choices (approach and avoidance) in response to negative and positive social cues (anger and joy) in 40 healthy volunteers using a computerized neuropsychological task, and to determine wheter these choices are the result of goal-directed behavior.

The study also aims to assess the modulation of behavioral adaptation by the level of impulsivity, lonilness, empathy, and by the capcity to understand others' intenstions.

Condition or Disease	Intervention/Treatment	Phase
Major Depressive Episode

Study Design

Study Type:

Observational

Anticipated Enrollment :

40 participants

Observational Model:

Cohort

Time Perspective:

Cross-Sectional

Official Title:

Behavioral Adaptation to Negative and Positive Social Signals in Healthy Volunteers

Actual Study Start Date :

Jun 1, 2021

Anticipated Primary Completion Date :

Jun 1, 2022

Anticipated Study Completion Date :

Dec 30, 2022

Outcome Measures

Primary Outcome Measures

Percentage of approach and avoidance behavior in response to positive (joy) and negative (anger) social signals [1 day]
Calculation of the proportion of avoidance vs. approach choices

Secondary Outcome Measures

Response time [1 day]
Computerized measurement of reaction time before clicking to make the avoidance or approach choice

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 65 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion criteria:

Being between 18 and 65 years old
Absence of psychiatric pathology over the entire life
Being able to understand the nature, purpose and methodology of the study

Exclusion criteria:

Mental retardation or sever medical co-morbidity
Sensory or cognitive disability
Pregnant or breastfeeding woman
Protection by law (guardianship or curatorship)
Deprivation of liberty (by judicial or administrative decision)
Exclusion period in relation to another protocol
Inability to understand, speak and write French

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University hospital	Montpellier		France	34295

Sponsors and Collaborators

University Hospital, Montpellier

Investigators

Study Director: Emilie Olie, MD PhD, University Hospital, Montpellier

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

University Hospital, Montpellier

ClinicalTrials.gov Identifier:

NCT04899609

Other Study ID Numbers:

RECHMPL21_0304

First Posted:

May 24, 2021

Last Update Posted:

Sep 8, 2021

Last Verified:

Sep 1, 2021

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by University Hospital, Montpellier

Emotion

Motivation

Decision making

Goal-director behavior

Study Results

No Results Posted as of Sep 8, 2021