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Angiographie and OCT in Macula and Retinal Diseases

Sponsor
Medical University of Vienna (Other)
Overall Status
Completed
CT.gov ID
NCT01603823
Collaborator
(none)
30
Enrollment
1
Location
37
Duration (Months)
0.8
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to investigate the morphological and angiological retinal changes in different macular diseases.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Recently, a new generation of OCT devices relying on spectral domain technology (SD-OCT) has been introduced and allows for higher-resolution imaging. Based on this technology we can identify variable changes at the retinal surface such as, retinal thickening with cyst formation, swelling in the inner and outer nuclear layers and subretinal fluid. The introduction of an eye-tracking mode has allowed a better insight into the development of retinal morphologic changes The aim of this study was to investigate the incidence and structural morphology of PCME after successful uncomplicated cataract surgery in patients with previous pars plana vitrectomy (PPV) and indocyanine green-assisted peeling of an epiretinal membrane and the internal limiting membrane (ILM).

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    30 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Study Start Date :
    Aug 1, 2008
    Actual Primary Completion Date :
    Feb 1, 2010
    Actual Study Completion Date :
    Sep 1, 2011

    Arms and Interventions

    Arm Intervention/Treatment
    Healthy volunteers
    St.p. Pars plana vitrectomy

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      18 Years to 90 Years
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      Yes
      Inclusion Criteria:
      • previous 23-gauge PPV and ILM peeling
      Exclusion Criteria:

      • history of branch retinal vein occlusion

      • central retinal vein occlusion

      • wet macular degeneration

      • diabetic retinopathy

      • uveitis or other inflammatory eye disease.

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 Medical University of Vienna Vienna Austria 1090

      Sponsors and Collaborators

      • Medical University of Vienna

      Investigators

      None specified.

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      Stefan Sacu, Assoc.Prof., Medical University of Vienna
      ClinicalTrials.gov Identifier:
      NCT01603823
      Other Study ID Numbers:
      • 10082007
      First Posted:
      May 22, 2012
      Last Update Posted:
      May 22, 2012
      Last Verified:
      May 1, 2012
      Keywords provided by Stefan Sacu, Assoc.Prof., Medical University of Vienna
      vitrectomy
      cataract
      macular edema
      Additional relevant MeSH terms:
      Macular Edema

      Study Results

      No Results Posted as of May 22, 2012