Spaced Retrieval as Treatment for Aphasia

Sponsor

Rotman Research Institute at Baycrest (Other)

Overall Status

Recruiting

CT.gov ID

NCT04623125

Collaborator

Heart and Stroke Foundation of Canada (Other)

Enrollment

Location

Arm

Anticipated Duration (Months)

1.3

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Spaced Repetition training has been found to be more effective than massed repetition for individuals with aphasia. This study seeks to examine the relative efficiency of three kinds of spacing for picture-naming training: traditional random presentation, non-adaptive spaced repetition, and adaptive spaced repetition.

Condition or Disease	Intervention/Treatment	Phase
Aphasia, Acquired Aphasia Primary Progressive	Behavioral: Spaced Retrieval Practice	N/A

Detailed Description

Participants undergo a screening evaluation including the Quick Aphasia Battery (administered via teleconferencing software), and a preliminary picture naming test of approximately 300 pictures, used to select individual items for treatment. Participants then undertake online picture naming training for 30 minutes a day, over two weeks. Pictures are repeated according to three different schedules to be compared: random presentation, non-adaptive spaced repetition, and adaptive spaced repetition. We compare the number of pictures successfully learned and the verbal reaction time for the pictures assigned to the three conditions.

Study Design

Study Type:

Interventional

Anticipated Enrollment :

20 participants

Allocation:

N/A

Intervention Model:

Single Group Assignment

Masking:

None (Open Label)

Primary Purpose:

Treatment

Official Title:

Spaced Retrieval as Treatment for Aphasia: Does Adaptive Spacing Enhance Picture Naming Performance?

Actual Study Start Date :

Oct 1, 2020

Anticipated Primary Completion Date :

Oct 1, 2021

Anticipated Study Completion Date :

Jan 1, 2022

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Spaced Repetition Two weeks (10 sessions) of online picture-naming training with 60 words.	Behavioral: Spaced Retrieval Practice Online picture-naming training with 60 words which the participant experiences word-retrieval difficulties. Cards are shuffled arranged by the computerized training program.

Arm

Intervention/Treatment

Experimental: Spaced Repetition

Two weeks (10 sessions) of online picture-naming training with 60 words.

Behavioral: Spaced Retrieval Practice

Online picture-naming training with 60 words which the participant experiences word-retrieval difficulties. Cards are shuffled arranged by the computerized training program.

Outcome Measures

Primary Outcome Measures

Change in Picture Naming performance across conditions [Change from baseline to post-intervention immediately after two weeks of daily sessions, and one month followup.]
Word retention assessed after treatment

Eligibility Criteria

Criteria

Ages Eligible for Study:

N/A and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

presence of a post-stroke word finding deficit (i.e. aphasia), or primary progressive aphasia.
ability to evaluate the correctness of one's own responses when subsequently provided the with the correct answer

Exclusion Criteria:

diagnosis of a neurological disorder other than post-stroke or primary progressive aphasia
inability to evaluate the correctness of ones responses when subsequently provided with the correct answer

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Baycrest Health Sciences	Toronto	Ontario	Canada	M6A 2E1

Sponsors and Collaborators

Rotman Research Institute at Baycrest
Heart and Stroke Foundation of Canada

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Jed A. Meltzer, Ph.D, Senior Scientist, Rotman Research Institute at Baycrest

ClinicalTrials.gov Identifier:

NCT04623125

Other Study ID Numbers:

16-43s

First Posted:

Nov 10, 2020

Last Update Posted:

Nov 10, 2020

Last Verified:

Nov 1, 2020

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Jed A. Meltzer, Ph.D, Senior Scientist, Rotman Research Institute at Baycrest

Adaptive Spaced-Retrieval

Aphasia

Anomia

Anki

Additional relevant MeSH terms:

Aphasia

Study Results

No Results Posted as of Nov 10, 2020