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Effect of Lifestyle on Caries and Apical Periodontitis

Sponsor
University of Siena (Other)
Overall Status
Completed
CT.gov ID
NCT06072742
Collaborator
(none)
149
Enrollment
1
Location
11
Actual Duration (Months)
13.6
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study aimed to link lifestyle factors (Mediterranean diet adherence, stress, sleep quality, physical activity) to caries and apical periodontitis in 149 university-based individuals. Data included clinical and radiographic assessments and lifestyle questionnaires. Statistical tests and logistic regression were employed to analyze the relationships between these factors and oral health conditions.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The aim of this study was to evaluate the association between lifestyle (adherence to the Mediterranean diet, stress, sleep quality, and level of physical activity) with the presence of caries and apical periodontitis (AP) in a University-based cohort of individuals.

    A total of 149 patients were included in this cross-sectional study. In addition to clinical (cold test, percussion test, evaluation of tooth mobility) and radiographic (bitewing Rx, periapical Rx, and OPT) parameters, validated questionnaires were used to investigate patient's lifestyle. Data on the number of decayed, missing, and filled teeth (DMFT score) and the severity of apical periodontitis (PAI score) were extrapolated from the available clinical and instrumental investigations. Shapiro-Wilk test was used to evaluate the normal distribution of data; Wilcoxon rank-sum test (Mann-Whitney) was used to compare continuous variables. Fisher's test was used to compare dichotomized variables. A logistic regression model was performed for the multivariate analysis.

    Study Design

    Study Type:
    Observational [Patient Registry]
    Actual Enrollment :
    149 participants
    Observational Model:
    Cohort
    Time Perspective:
    Cross-Sectional
    Official Title:
    Effect of Lifestyle on Caries and Apical Periodontitis: Results From a University-based Cross-sectional Study
    Actual Study Start Date :
    Sep 20, 2020
    Actual Primary Completion Date :
    Aug 20, 2021
    Actual Study Completion Date :
    Aug 20, 2021

    Outcome Measures

    Primary Outcome Measures

    1. Mediterranean diet [September 2020 and August 2021]

      adherence to Mediterranean Diet questionnaire (QueMD)

    2. Physical activity [September 2020 and August 2021]

      International Physical Activity Questionnaire (IPAQ)

    3. Stress [September 2020 and August 2021]

      Perceived Stress Score (PSS) questionnaire

    4. Sleep quality [September 2020 and August 2021]

      Pittsburgh Sleep Quality Index (PSQI) questionnaire

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 70 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • age between 18 and 70

    • Good general health status;

    • Ability and willingness to give written consent;

    • Presence of at least 6 teeth.

    Exclusion Criteria:

    • Age <18 years;

    • Pregnancy or lactation;

    • administration of antibiotics within the last 6 months;

    • Inability and unwillingness to give written consent

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Azienda Ospedaliera Universitaria Senese Siena Italy 53100

    Sponsors and Collaborators

    • University of Siena

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Simone Grandini, Professor, University of Siena
    ClinicalTrials.gov Identifier:
    NCT06072742
    Other Study ID Numbers:
    • LS002
    First Posted:
    Oct 10, 2023
    Last Update Posted:
    Oct 10, 2023
    Last Verified:
    Oct 1, 2023
    Individual Participant Data (IPD) Sharing Statement:
    Undecided
    Plan to Share IPD:
    Undecided
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Simone Grandini, Professor, University of Siena
    Apical periodontitis
    caries
    inflammation
    Endodontics
    lifestyle
    Additional relevant MeSH terms:
    Periodontitis
    Periapical Periodontitis
    Inflammation

    Study Results

    No Results Posted as of Oct 10, 2023