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Acute and Chronic Responses to Blood Pressure After Exercise

Sponsor
Federal University of Uberlandia (Other)
Overall Status
Completed
CT.gov ID
NCT03160989
Collaborator
(none)
14
Enrollment
1
Arm
7
Actual Duration (Months)

Study Details

Study Description

Brief Summary

The study will evaluate the variability of blood pressure in postmenopausal and hypertensive women after only one session and after training of ten weeks of combined physical exercises (aerobic and resisted).

Condition or Disease Intervention/Treatment Phase
  • Other: physical exercises
 N/A

Detailed Description

Before starting the training program, all the volunteers will sign the Free and Informed Consent Form (TCLE) and must present a medical certificate releasing the participation. In addition, the volunteers will respond to an anamnesis questionnaire and will undergo an anthropometric evaluation before the experimental sessions. The physical exercise program will be held three times a week for 10 weeks, containing aerobic exercise (exercise treadmill) and resistance exercises (bodybuilding). Initially, a familiarization of the ergometers used will be performed, followed by a session to evaluate the intensity of resistance exercise through a maximal repetition test (1RM), and a session to evaluate aerobic fitness through an incremental treadmill test.

Before starting the training, volunteers will perform a single exercise session, following the same exercise protocol. All the volunteers will be submitted to the evaluation of the blood pressure during 24 hours through the measurement of ambulatory blood pressure (ABPM) in three moments:

  • PR: pre-training rest - the volunteers will arrive at the laboratory, will be in rest for 15 minutes and after that they will place the ABPM, without having done any exercise.

  • PE: post exercise - upon arriving at the laboratory, the volunteers will be submitted to a single combined exercise session, will have a maximum interval of 20 minutes for the bath and will place the MAP device.

  • CR: rest after chronic training - after the end of the 10 weeks of training, the volunteers will be submitted to ABPM, again at rest, with a maximum interval of 72 hours, between the end of the training and the placement of the device.

Study Design

Study Type:
Interventional
Actual Enrollment :
14 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Health Services Research
Official Title:
Acute and Chronic Responses to Blood Pressure After Exercise
Actual Study Start Date :
May 1, 2016
Actual Primary Completion Date :
Sep 1, 2016
Actual Study Completion Date :
Dec 1, 2016

Arms and Interventions

Arm Intervention/Treatment
Experimental: Postmenopausal and hypertensive women

The intervention will consist of a single session and after ten weeks of combined physical exercises (aerobic and resisted). All volunteers will participate in the same procedure.

Other: physical exercises
The intervention will consist of a single session and after ten weeks of combined physical exercises (aerobic and resisted). All volunteers will participate in the same procedure.

Outcome Measures

Primary Outcome Measures

  1. Change in ambulatory blood pressure variability in ten weeks [After ten weeks and before ten weeks of exercise training]

    The ambulatory blood pressure measurement will be performed for 24 hours. With the information obtained in this measurement, blood pressure variability will be performed.

Secondary Outcome Measures

  1. Comparison resting blood pressure [After ten weeks and before ten weeks of exercise training]

    The resting blood pressure is performed after 15 minutes of sitting, measured three times and the mean is calculated for analysis

  2. Anthropometric assessments [After ten weeks and before ten weeks of exercise training]

    Body composition of the volunteers

Eligibility Criteria

Criteria

Ages Eligible for Study:
50 Years to 70 Years
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
No
Inclusion Criteria:

  • Women aged between 50 and 70 years;

  • Be in the postmenopausal phase;

  • Be able to practice physical exercise on treadmill and resistance exercises (bodybuilding).

  • Present stage 1 hypertension, according to the guidelines of the Brazilian Society of Hypertension

  • Make use of anti-hypertensive medication, except beta-blockers

  • Participants should be evaluated with a cardiologist beforehand and present a certificate attesting that they are able to perform physical activities.

  • Do not present physical problems or cardiovascular complications that prevent the performance of physical exercises.

Exclusion Criteria:

  • Make use of beta-blockers

  • Present history of stroke or acute myocardial infarction;

  • Smoking;

  • Present diagnosis of Diabetes Mellitus.

  • Present renal pathologies

  • Use hormone replacement therapies

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Federal University of Uberlandia

Investigators

  • Principal Investigator: LARISSA A SANTOS MATIAS, Graduate, Federal University of Uberlandia

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Larissa Aparecida Santos Matias, LARISSA APARECIDA SANTOS MATIAS - Principal Investigator, Federal University of Uberlandia
ClinicalTrials.gov Identifier:
NCT03160989
Other Study ID Numbers:
  • CEP UFU 002095/
First Posted:
May 19, 2017
Last Update Posted:
May 22, 2017
Last Verified:
May 1, 2017
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Larissa Aparecida Santos Matias, LARISSA APARECIDA SANTOS MATIAS - Principal Investigator, Federal University of Uberlandia
Blood pressure variability
Combined physical exercise
Hypertension
Additional relevant MeSH terms:
Hypertension

Study Results

No Results Posted as of May 22, 2017