BIOPULCER: When Asking the Indication of a Skin Biopsy From a Patient With a Leg Ulcer in Primary Care?
Study Details
Study Description
Brief Summary
Leg ulcers are frequent. There are no epidemiological studies available in France, but international studies estimate the prevalence between 0.045 and 0.63% of the total population, prevalence increases with age, reaching 5% of patients over 80 years. Extrapolating these prevalences in the French population between 28 000 and 395 000 people are affected in France a leg ulcer.
It is a costly disease. In 2001, a French study conducted among 800 physicians, including 85.7% of general practitioners, involving more than 1000 patients with venous ulcers, it was estimated that the total cost of treatment per patient average was 888 32 euros. This is truly a public health problem.
Leg ulcers are in 80% of cases of vascular causes (venous, arterial or arteriovenous mixed). However, there are rare causes of ulcers: skin carcinoma, infectious ulcers and vasculitis. These ulcers rare causes require specific treatments that can often heal. To diagnose, to perform a skin biopsy. Thus, the general practitioner must know when to put the indication for biopsy of a leg ulcer.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
Goal :
Analyzing the last 100 consecutive skin biopsies performed in patients carriers of chronic leg ulcers, followed in the vascular medicine department of the Hospital Saint Joseph Paris, to determine:
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The reasons which motivated the doctor make the indication of biopsy:
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Disease duration of ulcer
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Unusual clinical features
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Other signs associated with ulcer
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Absence of a satisfactory explanation vascular
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The pathological results Purpose: To clear a typical profile ulcers biopsy
Methodology :
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Retrospective, single-center,
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Acquisition of data: via the pathology laboratory of the hospital will be collected the last 100 consecutive biopsies performed with leg ulcers in vascular medicine department of the hospital Saint Joseph Paris, between 1 January 2013 and the October 1, 2013. Then be analyzed all paper and electronic records of these patients.
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Grid and Analysis:
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Patient histories,
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vascular profile of patients,
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clinical and chronological criteria of the ulcer,
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Other signs associated with ulcer
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Results of histological biopsies.
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The data will be made anonymous on the grid for collection by a numbering system 1 100.
Study Design
Outcome Measures
Primary Outcome Measures
- Assessment of disease duration of ulcer [Day 1 of ulceration to the day 30]
by calculating the number of days from ulceration to the healing
Eligibility Criteria
Criteria
Inclusion Criteria:
- The last 100 consecutive skin biopsies performed in patients carriers of chronic leg ulcers, hospitalized in the vascular medicine department of the Hospital Saint Joseph Paris
Exclusion Criteria:
- No exclusion criteria
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Groupe Hospitalier Paris Saint Joseph | Paris | Ile-de-France | France | 75014 |
Sponsors and Collaborators
- Groupe Hospitalier Paris Saint Joseph
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Biopsie cutanée