Assessment of Artificial Intelligence for Treatment Decision Recommendation of Adult Skeletal Class III Patients

Sponsor
Cairo University (Other)
Overall Status
Recruiting
CT.gov ID
NCT06002373
Collaborator
(none)
150
1
9.1
16.5

Study Details

Study Description

Brief Summary

The study titled "Reliability Of Artificial Intelligence for Treatment Decision Recommendation of Adult Skeletal Class III Patients" aims to assess the accuracy and dependability of artificial intelligence (AI) in providing treatment decision recommendations for adult patients with skeletal Class III malocclusion. Skeletal Class III malocclusion is characterized by an underdeveloped upper jaw or an overdeveloped lower jaw, leading to facial and dental irregularities. The study focuses on evaluating whether AI-based recommendations can reliably guide orthodontic treatment planning for this specific patient group.

This diagnostic test accuracy study involves collecting a diverse dataset of adult patients diagnosed with skeletal Class III malocclusion. AI algorithms will be trained on this dataset using various clinical and radiographic parameters to learn patterns and make treatment recommendations. The study will then compare the AI-generated treatment recommendations to those provided by experienced orthodontists.

Key aspects of the study include:

AI Reliability: The primary objective is to assess how consistently and accurately the AI system can recommend appropriate treatment decisions for adult skeletal Class III patients.

Diagnostic Test Accuracy: The study will determine the sensitivity, specificity, positive predictive value, and negative predictive value of the AI-generated treatment recommendations. This analysis will highlight the AI's ability to correctly identify patients who require specific treatment interventions.

Clinical Validity: Researchers will investigate whether the AI recommendations align with the decisions made by experienced orthodontists. This assessment is crucial to establish the AI system's clinical applicability.

Potential Benefits: If the AI system proves reliable and accurate, it could offer a time-efficient and standardized method for treatment decision support, aiding orthodontists in providing personalized care to adult skeletal Class III patients.

By conducting this study, researchers aim to contribute to the advancement of AI-assisted medical decision-making within the field of orthodontics. Successful outcomes would have the potential to revolutionize treatment planning processes, improve patient outcomes, and provide a valuable tool for orthodontists to make informed treatment decisions for adult skeletal Class III patients

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    150 participants
    Observational Model:
    Cohort
    Time Perspective:
    Retrospective
    Official Title:
    Reliability Of Artificial Intelligence for Treatment Decision Recommendation of Adult Skeletal Class III Patients: A Diagnostic Test Accuracy Study
    Actual Study Start Date :
    May 1, 2023
    Anticipated Primary Completion Date :
    Jan 1, 2024
    Anticipated Study Completion Date :
    Feb 1, 2024

    Outcome Measures

    Primary Outcome Measures

    1. sensitivity and specificity [1 month]

      the difference in sensitivity and specificity between the treatment decisions taken by the clinicians in comparison to those provided by the artificial intelligence software

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Skeletally mature patients with CVMI 6.

    • Skeletal class III patients

    • No congenital deformity, syndrome, or cleft.

    • No previous surgical intervention

    • No mandibular transverse functional shift.

    • Normal overjet, overbite after completion of treatment.

    • Patients with well finished occlusion.

    • Patients who have achieved adequate functional and aesthetic results at the end of their treatment.

    • Good quality initial and final lateral cephalometric radiographs.

    • No sex predilection.

    Exclusion Criteria:
    • Adolescents and skeletally immature patients.

    • Patients with pseudo class III.

    • Syndromic patients.

    • Patients with facial deformity at the naso-maxillary complex

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Cairo University Cairo Egypt

    Sponsors and Collaborators

    • Cairo University

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Maha Abd El-Monem Nasr, Principal Investigator, Cairo University
    ClinicalTrials.gov Identifier:
    NCT06002373
    Other Study ID Numbers:
    • 8114
    First Posted:
    Aug 21, 2023
    Last Update Posted:
    Aug 23, 2023
    Last Verified:
    Aug 1, 2023
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Aug 23, 2023