Assessment of Energy Expenditure by Indirect Calorimetry for a Daily 10,000 Steps Goal

Sponsor
National Taiwan University Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT00995579
Collaborator
(none)
20
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3
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Study Details

Study Description

Brief Summary

The purpose of this study was to measure the actual energy expenditure (EE) using indirect calorimetry for the 10,000 steps goal, and compared to the estimated EE using predictive equation.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Physical inactivity is considered a major risk factor for a number of adverse health outcomes such as obesity, hypertension, cardiovascular disease, diabetes mellitus, and all-cause mortality. Certain guidelines specifically recommend taking 10,000 steps per day for a goal. Some of pedometers have a function of energy expenditure estimation in addition to counting steps. However, the EE derived from pedometers is the indirect estimation calculated from metabolic calculations instead of direct measurement.The purpose of this study was to measure the actual energy expenditure (EE) using indirect calorimetry for the 10,000 steps goal, and compared to the estimated EE using predictive equation.

    Twenty healthy college volunteers were recruited. First, height and weight were measured from each subject. Body mass index (BMI) was calculated as the ratio of weight to height in meters squared. We used BioScan 920 to get all subjects' body composition data including fat mass and fat-free mass. Followed by measurements of basic characteristics, all subjects wore the pedometer and walked 10,000 steps on the treadmill. The walking speeds ranged from 3.0 to 4.0 miles per hour (mph) according to different gender. The speed of 4.0 mph was set for male and 3.0 mph was set for female. If the subject could'nt follow the pre-set speed, he/she could walk with self-comfortable speed but the speed should be in the range of 3.0 to 4.0 mph defined as moderate intensity of ACSM's recommendation. Subjects rested on the chair with back support for 3 minutes and then completed the 10,000 steps goal. After recovery for 3 minutes, the data collection was finished. The stopping criteria of the test were as follows: dizziness, nausea, dyspnea, or leg fatigue which leads subjects unable to continue. Expired gas was collected using the Cosmed K4b2 portable indirect calorimetry system, and EE was monitored breath-by-breath according to the following formula:

    EE (Kcal/min)= 3.781×VO2+1.237×VCO2

    where VO2 represents the standardized oxygen consumption per minute, and VCO2 is the carbon dioxide production per minute. Estimated EE was calculated by the predictive equation published by ACSM:

    VO2 (ml/kg/min)= 0.1×S (m/min)+1.8×S×G (%)+3.5

    where S represents the walking speed, and G is the walking grade.

    The total walking duration and distance for taking 10,000 steps were also recorded. Pulmonary function tests were performed on the other day to get each subject's functional vital capacity (FVC). We used this parameter to estimate subject's predicted maximal minute ventilation (predicted max VE) according to the equation provided in the guidelines of

    American Thoracic Society (ATS) for cardiopulmonary exercise testing:

    VE (L/min)= 26.3×VC-34

    where VC represents vital capacity. The ratio of averaged VE during walking and predicted maximal VE was calculated to determine the level of exercise intensity for taking 10,000 steps.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    20 participants
    Observational Model:
    Cohort
    Time Perspective:
    Cross-Sectional
    Official Title:
    Assessment of Energy Expenditure by Indirect Calorimetry for a Daily 10,000 Steps Goal
    Study Start Date :
    Nov 1, 2008
    Actual Primary Completion Date :
    Feb 1, 2009
    Actual Study Completion Date :
    Feb 1, 2009

    Arms and Interventions

    Arm Intervention/Treatment
    Healthy college volunteers

    Outcome Measures

    Primary Outcome Measures

    1. energy expenditure [3 months]

    Secondary Outcome Measures

    1. Body composition: fat mass and fat-free mass [3 months]

    2. Pulmonary function: FVC, FEV1, FEV1/FVC [3 months]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 30 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Aged 18-30 y/o
    Exclusion Criteria:
    • Unstable systemic disease, respiratory diseases, cardiac diseases or other clinical diagnosis which would affect outcome measure

    • Subjects who answered yes to any of the PAR-Q questions or who were not physically able to complete the test

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 School and Graduate Institute of Physical Therapy, National Taiwan University Taipei Taiwan

    Sponsors and Collaborators

    • National Taiwan University Hospital

    Investigators

    • Principal Investigator: Liying Wang, Ph.D., chool and Graduate Institute of Physical Therapy, National Taiwan University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00995579
    Other Study ID Numbers:
    • 200809081R
    First Posted:
    Oct 15, 2009
    Last Update Posted:
    Oct 15, 2009
    Last Verified:
    Oct 1, 2009
    Keywords provided by , ,

    Study Results

    No Results Posted as of Oct 15, 2009