Association Between Carotid Plaque Length and Cardiovascular Events

Sponsor

Changhai Hospital (Other)

Overall Status

Active, not recruiting

CT.gov ID

NCT05159804

Collaborator

Putuo Hospital, Shanghai University of Traditional Chinese Medicine (Other), No. 904 Hospital of the PLA Joint Logistics Support Force (Other), Gongli Hospital (Other), Yueyang Hospital, Shanghai University of Traditional Chinese medicine (Other)

3,637

Enrollment

Locations

167.9

Anticipated Duration (Months)

727.4

Patients Per Site

4.3

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This multicenter study involved 5 hospitals (Changhai Hospital; Yueyang Hospital of Shanghai University of Traditional Chinese Medicine; Gongli Hospital; Putuo Hospital of Shanghai University of Traditional Chinese Medicine; No. 904 Hospital of the PLA Joint Logistics Support Force Wuxi). The study enrolled 3637 patients with coronary atherosclerosis who were confirmed by coronary angiography from January 2017 through December 2018.

Condition or Disease	Intervention/Treatment	Phase
Coronary Arteriosclerosis

Detailed Description

Patients with coronary atherosclerosis who were confirmed by coronary angiography were eligible for the study. Carotid ultrasonography was simultaneously performed, and carotid intima-media thickness (IMT), maximum thickness and length of all plaques were measured.

Study Design

Study Type:

Observational

Actual Enrollment :

3637 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Association Between Carotid Plaque Length and Cardiovascular Events

Actual Study Start Date :

Jan 1, 2017

Actual Primary Completion Date :

Jun 30, 2021

Anticipated Study Completion Date :

Dec 30, 2030

Arms and Interventions

Arm	Intervention/Treatment
Carotid plaque length Patients underwent coronary angiography and carotid ultrasonography simultaneously

Outcome Measures

Primary Outcome Measures

Major adverse cardiovascular events [3 years]
A composite of cardiovascular death, myocardial infarction, and stroke

Secondary Outcome Measures

Incident cardiovascular events [3 years]
A composite of cardiovascular death, myocardial infarction, stroke, and unplanned coronary artery revascularization

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Patients≥18 years old, those who underwent carotid ultrasonography and first coronary angiography simultaneously.

Exclusion Criteria:

Patients with known coronary artery disease, previous coronary or carotid revascularization, missing carotid ultrasound or coronary angiography results.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	No. 904 Hospital of the PLA Joint Logistics Support Force	Wuxi	Jiangsu	China	214000
2	Changhai Hospital	Shanghai	Shanghai	China	200000
3	Gongli Hospital	Shanghai	Shanghai	China	200000
4	Putuo Hospital	Shanghai	Shanghai	China	200000
5	Yueyang Hospital	Shanghai	Shanghai	China	200000

Sponsors and Collaborators

Changhai Hospital
Putuo Hospital, Shanghai University of Traditional Chinese Medicine
No. 904 Hospital of the PLA Joint Logistics Support Force
Gongli Hospital
Yueyang Hospital, Shanghai University of Traditional Chinese medicine

Investigators

Principal Investigator: Pan Li, PhD, Changhai Hospital
Study Director: Jian Na, MD, Putuo Hospital
Study Director: Liang Chen, MD, No. 904 Hospital of the PLA Joint Logistics Support Force
Study Director: Wei Zhang, MD, Gongli Hospital
Study Director: Yawei Yang, MD, Yueyang Hospital