Association Between Uric Acid and Acute Coronary Syndrome

Sponsor

Sohag University (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT05770323

Collaborator

(none)

150

Enrollment

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

The aim of the study is to acess the association between admission serum uric acid level and in_hospital outcomes in patients with acute coronary syndromes

Condition or Disease	Intervention/Treatment	Phase
Acute Coronary Syndrome	Diagnostic Test: Uric acid level

Detailed Description

Prospective study

To acess patients with acute coronary syndrome including one of (typical Chest pain _ECGchanges _elevated cardic enzyme)
the complication occur in patients with hyperurecemia and those with normal uric acid

Study Design

Study Type:

Observational

Anticipated Enrollment :

150 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

The Association Between Serum Uric Acid Level and Acute Coronary Syndrome in_hospital Outcomes

Anticipated Study Start Date :

Mar 22, 2023

Anticipated Primary Completion Date :

Feb 22, 2024

Anticipated Study Completion Date :

Mar 22, 2024

Arms and Interventions

Arm	Intervention/Treatment
Patients with normal uric acid levels Patient with uric acid level (2.5_6)for femal and (3_7)for males	Diagnostic Test: Uric acid level Uric acid will be measured for all Patients with acute coronary syndrome and result will be analysed
Patients with elevated uric acid level (hyperurecemia) Uric acid level more than 7 for males and more than 6 for female	Diagnostic Test: Uric acid level Uric acid will be measured for all Patients with acute coronary syndrome and result will be analysed

Arm

Intervention/Treatment

Patients with normal uric acid levels

Patient with uric acid level (2.5_6)for femal and (3_7)for males

Diagnostic Test: Uric acid level

Uric acid will be measured for all Patients with acute coronary syndrome and result will be analysed

Patients with elevated uric acid level (hyperurecemia)

Uric acid level more than 7 for males and more than 6 for female

Diagnostic Test: Uric acid level

Uric acid will be measured for all Patients with acute coronary syndrome and result will be analysed

Outcome Measures

Primary Outcome Measures

Association between serum uric acid level and acute coronary syndrome in hospital outcomes [From the day of admission and 30 days post discharge]
Comparision between Patient with hyperurecemia and those with normal uric acid level

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

all patients with acute coronary syndrome with one of the Following

Typical Chest pain
ECG changes
Elevated cardiac enzyme

Exclusion Criteria:

patients aged less than 18 years
patients with gout
patients with treated with diuretics
Patient with CKD
Patient with chronic haemolytic anemia

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Sohag University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Maloberti A, Biolcati M, Ruzzenenti G, Giani V, Leidi F, Monticelli M, Algeri M, Scarpellini S, Nava S, Soriano F, Oreglia J, Sacco A, Morici N, Oliva F, Piani F, Borghi C, Giannattasio C. The Role of Uric Acid in Acute and Chronic Coronary Syndromes. J Clin Med. 2021 Oct 16;10(20):4750. doi: 10.3390/jcm10204750.

Responsible Party:

Hadeer Hassan Abdelaty, Resident doctor at sohag University, Sohag University

ClinicalTrials.gov Identifier:

NCT05770323

Other Study ID Numbers:

Uric acid in ACSs

First Posted:

Mar 15, 2023

Last Update Posted:

Mar 15, 2023

Last Verified:

Mar 1, 2023

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Acute Coronary Syndrome

Syndrome

Uric Acid

Study Results

No Results Posted as of Mar 15, 2023