Symbicort Onset of Action 2
Study Details
Study Description
Brief Summary
The purpose of this study is to compare the early onset of effect of Symbicort compared to Advair Diskus and Ventolin in adults with asthma
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
Phase 3 |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: 1 budesonide/formoterol |
Drug: budesonide/formoterol
Other Names:
|
Active Comparator: 2 fluticasone/salmeterol |
Drug: fluticasone/salmeterol
Other Names:
|
Active Comparator: 3 albuterol |
Drug: albuterol
Other Names:
|
Outcome Measures
Primary Outcome Measures
- FEV1 3 minutes post dose [4 assessments across 4 visits whilst on treatment (visits may be between 3 and 14 days apart)]
Secondary Outcome Measures
- 12 hour serial FEV1 [4 assessments across 4 visits whilst on treatment (visits may be between 3 and 14 days apart)]
- Patients perception of effect [Patients perception of effect]
Eligibility Criteria
Criteria
Inclusion Criteria:
-
At least 18 years of age
-
Diagnosis of asthma and baseline lung function test results as determined by the protocol
-
Required and received inhaled corticosteroids within timeframe and doses specified in the protocol
Exclusion Criteria:
-
Severe asthma or asthma that is markedly effected by seasonal factors
-
Has required and received non-inhaled corticosteroids within the previous 4 weeks, has sensitivity to drugs specified in the protocol or requires treatment with beta-blockers
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- AstraZeneca
Investigators
- Study Director: Catherine Bonuccelli, AstraZeneca
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- SD-039-0733
- D5896C00733