The Acute Effects of Combined Caffeine and Sodium Bicarbonate Consumption on Isometric Mid-thigh Pull

Sponsor
Bozok University (Other)
Overall Status
Completed
CT.gov ID
NCT05883046
Collaborator
(none)
19
1
5
5
115.7

Study Details

Study Description

Brief Summary

The aim of this study was to investigate the effects of isolated and combined caffeine and sodium bicarbonate consumption on acute isometric mid-thigh pull (IMTP) strength, and verify whether they are cumulative, neutral or subtractive.

Condition or Disease Intervention/Treatment Phase
  • Other: Performance-Enhancing Substances
  • Other: Placebo
  • Other: Baseline (Control)
N/A

Detailed Description

Method: Nineteen Sport Sciences Faculty students (Age 23.6±1.6 years, height 171±9.4 cm, weight 64.3±9.6 kg, fat percentage 20.5±7.3 %, BMI 21.7±2.4 kg/m2) participated and completed the intervention. This study was designed as crossover, double-blind and placebo-controlled. Subjects participated under 5 crossover conditions: control (without supplement) (Con), placebo (Pla), caffeine (Caf), sodium bicarbonate (NaHCO3) and caffeine+sodium bicarbonate (Caf+NaHCO3). For Caf conditions, participants consumed 6 mg/kg of caffeine, obtained from dosing the content of 200 mg capsules. As for NaHCO3 conditions, participants consumed 0.3 g/kg of sodium bicarbonate dissolved in water. For the combined condition, (Caf+NaHCO3), intake was set at 6 mg of caffeine and 0.3 g of sodium bicarbonate per kilogram of body weight. All supplements were consumed 60 min before the tests. Two submaximal trials of IMTP were performed at increasing intensities for 5 seconds (approximately %40-60 and %60-80 of their individually perceived 1RM, respectively, with 60-second rest intervals).

Study Design

Study Type:
Interventional
Actual Enrollment :
19 participants
Allocation:
Non-Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
subjects participated under 5 crossover conditions: control (without supplement) (Con), placebo (maltodextrin) (Pla), caffeine (Caf), sodium bicarbonate (NaHCO3) and caffeine+sodium bicarbonate (Caf+NaHCO3). The control measurement was made as a baseline measurement without supplementation.subjects participated under 5 crossover conditions: control (without supplement) (Con), placebo (maltodextrin) (Pla), caffeine (Caf), sodium bicarbonate (NaHCO3) and caffeine+sodium bicarbonate (Caf+NaHCO3). The control measurement was made as a baseline measurement without supplementation.
Masking:
Double (Participant, Investigator)
Masking Description:
Supplement preparation, as well as the provision and management of blind conditions for both participants and investigators, were performed by a researcher (Celil KAÇOĞLU) who did not participate in the strength measurements.
Primary Purpose:
Other
Official Title:
The Acute Effects of Pre-Exercise Isolated and Combined Caffeine and Sodium Bicarbonate Consumption on Isometric Mid-thigh Pull Performance: A Placebo-Controlled Study
Actual Study Start Date :
Mar 7, 2022
Actual Primary Completion Date :
Mar 8, 2022
Actual Study Completion Date :
Mar 12, 2022

Arms and Interventions

Arm Intervention/Treatment
Other: Baseline

The control measurement was made as a baseline measurement without supplementation

Other: Baseline (Control)
No supplement conditions

Placebo Comparator: Placebo

During Placebo conditions, participants consumed 20gr of maltodextrin (European origin, Alfasol®, Kimbiotek, Turkey).

Other: Placebo
20gr of maltodextrin (European origin, Alfasol®, Kimbiotek, Turkey)

Experimental: Caffeine

For Caffeine conditions, participants consumed 6 mg/kg of caffeine, obtained from dosing the content of 200 mg capsules (Nature's Supreme® Caffeine)

Other: Performance-Enhancing Substances
All supplements were consumed 60 min before the isometric mid-thigh pull tests, to reach peak blood concentrations at evaluation time. Immediately after consumption, both Control and intervention participants rested in a quiet laboratory environment (Eskişehir Technical University, Laboratory of Human Athletic Performance), until the strength tests. Participants were previously informed verbally and in writing that they should abstain from caffeine consumption (any caffeine-containing beverages and foods, such as coffee or tea, energy drinks, cocoa and cocoa-containing foods, chocolate and chocolate-containing foods or caffeine-containing drugs) for at least 24 hours before

Experimental: NaHCO3

As for NaHCO3 conditions, participants consumed 0.3 g/kg of sodium bicarbonate (Alfasol®, Kimbiotek, Turkey) dissolved in water

Other: Performance-Enhancing Substances
All supplements were consumed 60 min before the isometric mid-thigh pull tests, to reach peak blood concentrations at evaluation time. Immediately after consumption, both Control and intervention participants rested in a quiet laboratory environment (Eskişehir Technical University, Laboratory of Human Athletic Performance), until the strength tests. Participants were previously informed verbally and in writing that they should abstain from caffeine consumption (any caffeine-containing beverages and foods, such as coffee or tea, energy drinks, cocoa and cocoa-containing foods, chocolate and chocolate-containing foods or caffeine-containing drugs) for at least 24 hours before

Experimental: Combined

For the combined condition, (Caf+NaHCO3), 6 mg/kg of caffeine and 0.3 g/kg of sodium bicarbonate per kilogram of body weight of participants were consumed, after being dissolved together in water

Other: Performance-Enhancing Substances
All supplements were consumed 60 min before the isometric mid-thigh pull tests, to reach peak blood concentrations at evaluation time. Immediately after consumption, both Control and intervention participants rested in a quiet laboratory environment (Eskişehir Technical University, Laboratory of Human Athletic Performance), until the strength tests. Participants were previously informed verbally and in writing that they should abstain from caffeine consumption (any caffeine-containing beverages and foods, such as coffee or tea, energy drinks, cocoa and cocoa-containing foods, chocolate and chocolate-containing foods or caffeine-containing drugs) for at least 24 hours before

Outcome Measures

Primary Outcome Measures

  1. Isometric Mid-Thigh Pull (IMTP) [immediately after the intervention]

    to investigate the effects of isolated and combined caffeine and sodium bicarbonate consumption on acute isometric mid-thigh pull (IMTP) strength, and verify whether they are cumulative, neutral or subtractive

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 24 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Being physically active and healthy

  • Did not use ergogenic supplements in the last 3 months

  • Did not consume high doses of caffeine (≤120-170 mg/d) were included in this study

Exclusion Criteria:
  • Actively using supplements

  • Did not perform maximal effort during performance tests

  • Not using the supplements in the correct dose or vomiting after use

Contacts and Locations

Locations

Site City State Country Postal Code
1 Faculty of Sport Sciences Eskisehir Technical University Eskişehir Tepebasi Turkey 26555

Sponsors and Collaborators

  • Bozok University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Izzet Kirkaya, Associate Professor, Bozok University
ClinicalTrials.gov Identifier:
NCT05883046
Other Study ID Numbers:
  • BozokU-SBF-IK-01
First Posted:
May 31, 2023
Last Update Posted:
May 31, 2023
Last Verified:
May 1, 2023
Individual Participant Data (IPD) Sharing Statement:
Yes
Plan to Share IPD:
Yes
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Izzet Kirkaya, Associate Professor, Bozok University
Additional relevant MeSH terms:

Study Results

No Results Posted as of May 31, 2023