LACROSS: Cardiovascular Registry of Atrial Fibrillation
Study Details
Study Description
Brief Summary
Follow a representative sample of Latin American patients diagnosed with atrial fibrillation to set data on demographic characteristics, documenting antithrombotic therapy, describe the INR control level of VKA users, discontinuation rates and clinical outcomes, such as stroke, hemorrhage and death
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
Patients will be followed 6 months and 1 year after the baseline visit and will be collected data of antithrombotic therapy, laboratory data, discontinuation rates of antithrombotic therapy and clinical outcomes.
Study Design
Outcome Measures
Primary Outcome Measures
- INR control rate [12 months]
- Oral anticoagulation discontinuation rate [12 months]
- Percentage of death [12 months]
- Percentage of stroke [12 months]
- Percentage of systemic embolism [12 months]
- Percentage of myocardial infarction [12 months]
- Percentage of major bleeding [12 months]
- Percentage of electrical cardioversion [12 months]
- Percentage of percutaneous ablation of AF [12 months]
- Percentage of atrioventricular junction ablation [12 months]
- Percentage of patients that need of pacemaker implantation [12 monts]
- Percentage of other cardiovascular hospitalization [12 months]
Eligibility Criteria
Criteria
Inclusion Criteria:
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Age > 18 years-old that signed informed consent;
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Atrial Fibrillation or Atrial Flutter at the time of inclusion documented in source document;
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If the patient is not in atrial fibrillation or Atrial Flutter rhythm, s/he should have 2 electrographic records, at least 15 days apart between them, with one of them being performed within the last 6 months before enrollment (AF may be documented by 12-lead ECG, Holter monitor-24h);
Exclusion Criteria:
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Patients who did not agree to participate.
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Patients without possibility of monitoring for one year.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hospital Interzonal General de Agudos "Dr. José Penna" | Bahía Blanca | Buenos Aires | Argentina | |
| 2 | DIM Clínica Privada | Ramos Mejía | Buenos Aires | Argentina | |
| 3 | Centro de Investigaciones Medicas Temperley (CIMeT) | Temperley | Buenos Aires | Argentina | |
| 4 | Hospital Italiano de La Plata | Buenos Aires | La Plata | Argentina | |
| 5 | Centro Modelo de Cardiologia | San Miguel De Tucumán | Tucumán | Argentina | |
| 6 | Centro Medico Luquez | Córdoba | Argentina | ||
| 7 | Prevención Cardiovascular Salta | Salta | Argentina | ||
| 8 | Servicios Médicos El Castaño | San Juan | Argentina | ||
| 9 | Instituto Cardiovascular San Luis | San Luis | Argentina | ||
| 10 | Centro de Investigaciones Clinicas del Litoral SRL | Santa Fe | Argentina | ||
| 11 | Hospital Provincial Dr. José Maria Cullen | Santa Fe | Argentina | ||
| 12 | Hospital Alvorada Taguatinga Ltda | São Paulo | Brazil | ||
| 13 | Sociedad de Cirugia de Bogota - Hospital de San Jose | Bogotá | Cundinamarca | Colombia | |
| 14 | Fundacion Valle del Lili | Cali | Valle Del Cauca | Colombia | |
| 15 | Francisco Gerardo Padilla Padilla | Guadalajara | Jalisco | Mexico | |
| 16 | Centro de Estudios Clínicos de Queretaro S.C. (CECLIQ) | Querétaro City | Querétaro | Mexico | |
| 17 | Centro para el Desarrollo de la Medicina y de Asistecia Medica Especializada S.C. | Culiacán | Sinaloa | Mexico |
Sponsors and Collaborators
- Brazilian Clinical Research Institute
Investigators
- Study Chair: Renato D. Lopes, MD, PhD, Instituto Brasileiro de Pesquisa Thomaz de Carvalho - BCRI
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 001/2018