AUSSIE-1: Australian UCSF Concussion in Athletes
Study Details
Study Description
Brief Summary
Analysis of cardiac induced brain forces using cranial accelerometry has been shown to diagnose concussion in high school athletes. This trial expands on this observation by recording headpulse signals in a recently concussed athletes playing Australian rules football.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Detailed Description
Recently concussed athletes will have headpulse measurements obtained as soon after the clinically identified concussion as is feasible and at 1-3 day intervals over the course of a month. These recordings will pair with a self administered neurological symptom inventory (NSI) to track the athletes subjective concussion symptoms. Data will be used to confirm prior models of analysis and produce a tool to be confirmed in a future study.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Concussed Diagnosis of concussion |
Device: Headpulse measurements
Placement of headset on subject
|
Controls Athletes with no concussion within the preceding year |
Device: Headpulse measurements
Placement of headset on subject
|
Outcome Measures
Primary Outcome Measures
- Sensitivity of headpulse measurements to detect subjects with concussion [1 month]
Proportion of clinically concussed athletes that have headpulse values > 2SD of control subjects
Secondary Outcome Measures
- Feasibility of subject recruitment [2.5 months]
Number of subjects recruited during playoff season
Eligibility Criteria
Criteria
Concussion Subjects:
Inclusion Criteria:
-
Diagnosed with sport related concussion
-
first recording obtained within one week
-
willingness to have multiple recordings in the month following concussion
Exclusions:
- head laceration
Control subjects:
Inclusion Criteria:
-
athletes without concussion over the last year
-
willingness to have single or multiple recordings
Exclusion Criteria:
- head laceration
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | UCSF | San Francisco | California | United States | 94143 |
Sponsors and Collaborators
- University of California, San Francisco
Investigators
- Principal Investigator: Wade S Smith, MD, PhD, University of California, San Francisco
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 1572