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MEM-T2A: Associative Memory in Adults With an Autism Spectrum Disorder

Sponsor
University Hospital, Caen (Other)
Overall Status
Unknown status
CT.gov ID
NCT02279680
Collaborator
(none)
40
Enrollment
1
Location
2
Arms
30
Duration (Months)
1.3
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The objective of this multidisciplinary project is to explore the deficit of associative memory in ASD (Autistic Spectrum Disorder) that could result from abnormal brain connectivity. The hypothesis of abnormal functioning of the fronto-hippocampal network has been evocated but has never been tested. Hence, the present project will include two complementary assessments conducted on a group of adults aged from 18 to 30 with ASD compared to a control group matched in chronological age and intellectual quotient. The first assessment is devoted to the study of associative memory and its EEG correlates and the second focused on the investigation of perceptual strategies related to associative memory using the technique of Eye-tracking. Both behavioral and imaging data would provide new insights on the relationship between perception and memory in ASD.

Condition or Disease Intervention/Treatment Phase
  • Device: Electroencephalography
  • Behavioral: Neuropsychological assesments
 N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
40 participants
Allocation:
Non-Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Health Services Research
Official Title:
The Associative Memory in Autism Spectrum Disorders Without Intellectual Disability
Study Start Date :
Jun 1, 2014
Anticipated Primary Completion Date :
Dec 1, 2015
Anticipated Study Completion Date :
Dec 1, 2016

Arms and Interventions

Arm Intervention/Treatment
Other: Patients

Adults between 18 and 30 years old right handing Patients with ASD

Device: Electroencephalography

Behavioral: Neuropsychological assesments
Other: Healthy volunteers

Adults between 18 and 30 years old Right handing Healthy

Device: Electroencephalography

Behavioral: Neuropsychological assesments

Outcome Measures

Primary Outcome Measures

  1. The associative memory index [2 years]

Secondary Outcome Measures

  1. theta and gamma oscillations during the associative memory task [2 years]

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 30 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:

  • Adult between 18 and 30 years old

  • right handed

  • affiliated to the french national health care system

  • ASD only for the group of patients

Exclusion criteria :

  • mental retardation

  • schizophrenia

  • ADHD

  • brain injury with lost of consciousness

  • neurological disease

Contacts and Locations

Locations

Site City State Country Postal Code
1 UMR1077 Inserm/EPHE/UCBN Caen France 14000

Sponsors and Collaborators

  • University Hospital, Caen

Investigators

  • Principal Investigator: Jean-Marc BALEYTE, PU-PH, University Hospital, Caen

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
University Hospital, Caen
ClinicalTrials.gov Identifier:
NCT02279680
Other Study ID Numbers:
  • 2013-AO1800-45
First Posted:
Oct 31, 2014
Last Update Posted:
Oct 31, 2014
Last Verified:
Oct 1, 2014
Additional relevant MeSH terms:
Autism Spectrum Disorder
Autistic Disorder

Study Results

No Results Posted as of Oct 31, 2014