MEM-TA: Associative Memory in Autism Spectrum Disorder

• Sponsor: University Hospital, Caen (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT02265094
• Collaborator: Institut National de la Santé Et de la Recherche Médicale, France (Other), Amiens University Hospital (Other)
• Enrollment: 80
• Location: 1
• Arms: 2
• Anticipated Duration (Months): 47.3
• Patients Per Site Per Month: 1.7

Study Details

Study Description

Brief Summary

The aim of this study is to investigate the neural substrates of associative memory in Autism Spectrum Disorder using both behavioural and EEG assessments.

Condition or Disease	Intervention/Treatment	Phase
Autistic Disorder	Other: Electroencephalography; Behavioral: Neuropsychological assessment	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 80 participants
• Allocation: Non-Randomized
• Intervention Model: Factorial Assignment
• Masking: None (Open Label)
• Primary Purpose: Basic Science
• Official Title: Associative Memory in ASD Without Mental Retardation : Study in EEG and Neuropsychology
• Actual Study Start Date: Dec 22, 2015
• Anticipated Primary Completion Date: Dec 1, 2018
• Anticipated Study Completion Date: Dec 1, 2019

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Patients Electroencephalography and neuropsychological tests in children with autism	Other: Electroencephalography; EEG recordings during memory tests; Behavioral: Neuropsychological assessment; patterns of eye gaze during cognitive tests
Experimental: Control Electroencephalography and neuropsychological tests in children without autism	Other: Electroencephalography; EEG recordings during memory tests; Behavioral: Neuropsychological assessment; patterns of eye gaze during cognitive tests

Outcome Measures

Primary Outcome Measures

1. Index of discrimination obtained with the task of associative memory [4 years]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 10 Years to 18 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• Right handed children from 10 to 18 years old

• Informed consent signed by the legal representative and adolescent himself.

• Medical Examinations, psychopathology, and cognitive examination in accordance with inclusion and exclusion criteria specific to each population:

• People with ASD:

• Participants with ASD without mental retardation with a diagnosis in reference to the DSM V criteria

• Controls : Participants without ASD

Main exclusion criteria:

• mental retardation,

• schizophrenia,

• ADHD,

• head injury with lost of consciousness

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Caen University Hospital	Caen		France

Sponsors and Collaborators

• University Hospital, Caen
• Institut National de la Santé Et de la Recherche Médicale, France
• Amiens University Hospital

Investigators

• Principal Investigator: Jean-Marc BALEYTE, MD, University Hospital, Caen

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: University Hospital, Caen
• ClinicalTrials.gov Identifier: NCT02265094
• Other Study ID Numbers: 2014- A00481-46
• First Posted: Oct 15, 2014
• Last Update Posted: Feb 20, 2018
• Last Verified: Feb 1, 2018

• Keywords provided by University Hospital, Caen: Autism Spectrum Disorder; Development; Memory; ERD
• Additional relevant MeSH terms: Autism Spectrum Disorder; Autistic Disorder

Study Results

No Results Posted as of Feb 20, 2018