Autistic Features in Relation to Motor Function and Quality of Life in Children With an Autism Spectrum Disorder

Sponsor
Cairo University (Other)
Overall Status
Completed
CT.gov ID
NCT05650489
Collaborator
(none)
40
1
31.2
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Study Details

Study Description

Brief Summary

Although motor limitations are not currently considered a as clinical manifestation of autism spectrum disorder, they should not be ignored due to their high incidence and considerable influence on life quality functional activity

Condition or Disease Intervention/Treatment Phase
  • Other: assessment

Study Design

Study Type:
Observational
Actual Enrollment :
40 participants
Observational Model:
Other
Time Perspective:
Cross-Sectional
Official Title:
Autistic Features in Relation to Motor Function and Quality of Life in Children With an Autism Spectrum Disorder
Actual Study Start Date :
Apr 15, 2020
Actual Primary Completion Date :
Nov 20, 2022
Actual Study Completion Date :
Nov 20, 2022

Outcome Measures

Primary Outcome Measures

  1. Autism Index [baseline assessment]

    Gilliam autism rating scale: Items on the developmental subscale address behaviors and milestones in the first 36 months of life. Items on the first three behavioral subscales are rated on a four point like scale ranging from Never Observed (0) to Frequently Observed (3). After completing it, the examiner calculated the total raw scores then converted into scaled scores and percentile ranks according to the examiner's manual. Higher scaled scores on a subscale represent severe autistic behavior. Finally, the total scaled scores were calculated to measure the autism index according to the examiner's manual. The higher the autism index, the higher the probability the individual has autism and the more severe the autistic behavior

  2. Motor Development [baseline assessment]

    The Peabody Developmental Motor Scales-Second Edition: The gross motor function domain will be assessed in the current study. The gross motor function domains contain four subtests. Reflexes, Stationary ,Locomotion and Object Manipulation . Grading and Scoring of the PDMS-2 The therapist will ask the child to do a specific item and observes how the child is doing the task. Items are scored as 2, 1 or 0. 0 = child cannot or will not attempt an item or the attempt does not indicate that the specific skill is emerging child's performance shows a clear resemblance to item mastery criteria but does not fully meet the criteria or there are signs of an emerging skill child performs item according to the criteria specified for mastering the skill

  3. Pediatric Quality of life Inventory Scale [baseline assessment]

    Pediatric Quality of life Inventory Scale: The Arabic version will be used to assess quality of life. It contains questions about child's physical, emotional, social, and school functioning in the past 7 days. Parents/ child self-administered the quality of life after introductory instructions from the administrator. On the quality of life Generic Core Scales, for ease of interpretability, items are 22 reversed scored and linearly transformed to a 0-100 scale, so that higher scores indicate better Health-Related quality of Life. To reverse score, transform the 0-4 scale items to 0-100 as follows: 0-100, 1=75, 2= 50, 3= 25 and 4= 0. Finally, the Scale Score for each dimension and Total Scale Score were calculated

Eligibility Criteria

Criteria

Ages Eligible for Study:
3 Years to 5 Years
Sexes Eligible for Study:
All
Inclusion Criteria:
  • Both sex,

  • age ranges from 3 to 5 years,

  • mild to moderate autistic features according to childhood autism rating scale ,

  • they were able to sit alone independently

Exclusion Criteria:
  • Significant visual or auditory defects,

  • history of cerebral palsy or psychiatric disorder (e.g attention deficit hyperactivity disorder)

Contacts and Locations

Locations

Site City State Country Postal Code
1 Amira Mahmoud Abd-elmonem Giza Egypt 12662

Sponsors and Collaborators

  • Cairo University

Investigators

  • Principal Investigator: Eman s Albadry, B.S.C, Cairo university, faculty of physical therapy
  • Principal Investigator: MAI A OTHMAN, Sohag University
  • Study Chair: MAI E ABBASS, Cairo university, faculty of physical therapy

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Amira Mahmoud Abd-elmonem, Assist Prof. Physiacl therapy for pediatric department, faculty of physical therapy , Cairo university, Cairo University
ClinicalTrials.gov Identifier:
NCT05650489
Other Study ID Numbers:
  • Autism
First Posted:
Dec 14, 2022
Last Update Posted:
Dec 14, 2022
Last Verified:
Dec 1, 2022
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Amira Mahmoud Abd-elmonem, Assist Prof. Physiacl therapy for pediatric department, faculty of physical therapy , Cairo university, Cairo University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Dec 14, 2022