Autoantibodies Against Specific Cytokines in Adults With Severe Mycobacterial Infection
Sponsor
China Medical University Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT01628744
Collaborator
(none)
100
1
47
2.1
Study Details
Study Description
Brief Summary
In adult, the prevalence of mycobacterial infections is increased with age is largely unknown. IFN-gamma-IL-12/23 axis or NF-kappaB pathways might also plays crucial roles in adult against mycobacteria. Based on this hypothesis, the investigators had applied a functional assay to these pathways in patients with mycobacterial infection.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
100 participants
Observational Model:
Case-Only
Time Perspective:
Retrospective
Study Start Date
:
Jan 1, 2011
Anticipated Study Completion Date
:
Dec 1, 2014
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Patients with mycobacterial infection
|
Outcome Measures
Primary Outcome Measures
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- Patients with mycobacterial infection
Exclusion Criteria:
-
Malignancy
-
Severe autoimmune
-
HIV infection
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Graduate Institute of Clinical Medical Science, China Medical University | Taichung | Taiwan |
Sponsors and Collaborators
- China Medical University Hospital
Investigators
- Principal Investigator: Cheng-Lung KU, Ph.D, Graduate Institute of clinical Medical Science, China Medical Univerity, Taiwan
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
China Medical University Hospital
ClinicalTrials.gov Identifier:
NCT01628744
Other Study ID Numbers:
- DMR-99-IRB-075-1
First Posted:
Jun 27, 2012
Last Update Posted:
Jun 27, 2012
Last Verified:
Jun 1, 2012