Enthesis Differences in Rheumatoid Arthritis and Axial Spondyloarthropathy

Sponsor

Istanbul Training and Research Hospital (Other)

Overall Status

Enrolling by invitation

CT.gov ID

NCT05942976

Collaborator

(none)

106

Enrollment

Location

1.5

Anticipated Duration (Months)

70.1

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The aim of this study is to investigate the sonographic differences in entheses in patients with Rheumatoid arthritis and Axial Spondyloarthropathy.

Condition or Disease	Intervention/Treatment	Phase
Axial Spondyloarthritis Rheumatoid Arthritis Enthesitis Enthesopathy	Other: ULTRASOUND

Detailed Description

After recording the demographic data of the patients; 5 enthesis regions 5 enthesis sites were evaluated bilaterally as ''tricipital tendon (TT), quadricipital tendon (QT), proximal patellar tendon (PPT), distal patellar tendon (DPT), achilles tendon (AT)'' will be sonographically evaluated and the presence of hypoechogenicity , tendon thickness increase, power Doppler activity, erosion, presence of entezophyte/calcification will be investigated. The differences between the groups will then be compared.

Study Design

Study Type:

Observational [Patient Registry]

Anticipated Enrollment :

106 participants

Observational Model:

Cohort

Time Perspective:

Cross-Sectional

Official Title:

Ultrasonographic Differences in Entheses in Rheumatoid Arthritis and Axial Spondyloarthropathy Patients

Actual Study Start Date :

Jun 16, 2023

Anticipated Primary Completion Date :

Jul 15, 2023

Anticipated Study Completion Date :

Aug 1, 2023

Arms and Interventions

Arm	Intervention/Treatment
group 1: axial spondyloarthritis SpA patients identified according to the Assessment of Spondyloarthritis classification criteria	Other: ULTRASOUND 10 enthesis areas will be evaluated in 20 minutes with ultrasound.
group 2: Rheumatoid arthritis RA patients identified according to the 2010 American College of Rheumatology/Europan Leage Against Rheumatism classification criteria	Other: ULTRASOUND 10 enthesis areas will be evaluated in 20 minutes with ultrasound.
group:3 Healthy Control healthy controls with no history of rheumatic diseases	Other: ULTRASOUND 10 enthesis areas will be evaluated in 20 minutes with ultrasound.

Arm

Intervention/Treatment

group 1: axial spondyloarthritis

SpA patients identified according to the Assessment of Spondyloarthritis classification criteria

Other: ULTRASOUND

10 enthesis areas will be evaluated in 20 minutes with ultrasound.

group 2: Rheumatoid arthritis

RA patients identified according to the 2010 American College of Rheumatology/Europan Leage Against Rheumatism classification criteria

Other: ULTRASOUND

10 enthesis areas will be evaluated in 20 minutes with ultrasound.

group:3 Healthy Control

healthy controls with no history of rheumatic diseases

Other: ULTRASOUND

10 enthesis areas will be evaluated in 20 minutes with ultrasound.

Outcome Measures

Primary Outcome Measures

Ultrasound enthesis differences between the groups [2 months]
triceps tendon, quadriceps tendon, proximal patellar tendon, distal patellar tendon and achilles tendons enthesitis scores differences between the groups
The relationship between ultrasound findings and disease parameters [2 months]
The relationship between triceps tendon, quadriceps tendon, proximal patellar tendon, distal patellar tendon and achilles tendons enthesitis scores and Clinical disease activity index and BASDAI

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 65 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Rheumatoid arthritis patients identified according to the 2010 American College of Rheumatology /Europan Leage Against Rheumatism classification criteria,
axial Spondyloarthrtis patients identified according to the Assessment of Spondyloarthritis classification criteria
healthy controls with no history of rheumatic diseases.