Beneficial Effects of Microsurgical Varicocelectomy on Semen Parameters for Causes Other Than Infertility

• Sponsor: Seoul National University Hospital (Other)
• Overall Status: Completed
• CT.gov ID: NCT02006316
• Collaborator: (none)
• Enrollment: 121
• Location: 1
• Duration (Months): 122
• Patients Per Site Per Month: 1

Study Details

Study Description

Brief Summary

The purpose of this study is to evaluate whether clinical varicoceles are associated with abnormal semen parameters and whether varicocelectomy could improve the semen parameter in patients unrelated with infertility.

Condition or Disease	Intervention/Treatment	Phase
Varicocele	Procedure: Microsurgical subinguinal varicocelectomy

Detailed Description

While most studies are continued to validate the observations of significant improvements in sperm density and motility after varicocele ligation in infertile patients, there have been few studies to investigate the effects of varicocelectomy on semen parameters in adult men unrelated with infertility. The purpose of this study was to determine whether varicocelectomy could improve the semen parameter of these patients as well as whether clinical varicoceles are associated with abnormal semen parameters in patients unrelated with infertility.

Study Design

• Study Type: Observational
• Actual Enrollment: 121 participants
• Observational Model: Case-Only
• Time Perspective: Retrospective
• Official Title: Beneficial Effects of Microsurgical Varicocelectomy on Semen Parameters in Patients Who Underwent Surgery for Causes Other Than Infertility
• Study Start Date: Jan 1, 2000
• Actual Primary Completion Date: Apr 1, 2008
• Actual Study Completion Date: Mar 1, 2010

Arms and Interventions

Arm	Intervention/Treatment
varicoceles men with clinical varicoceles underwent microsurgical varicocelectomy due to causes other than infertility such as testicular pain, discomfort or scrotal mass	Procedure: Microsurgical subinguinal varicocelectomy

Outcome Measures

Primary Outcome Measures

1. Sperm concentration, motility, and morphology [at postoperative 4months]

   To observe the change of sperm concentration, motility, and morphology pre and postoperatively in the patients of inclusion criteria

Secondary Outcome Measures

1. whether semen analysis should be done in men with clinical varicocele regardless of the chief complaint [at postoperative 4months]

   this result would show the need of performing semen analysis even in the patients with clinical varicocels due to causes other than infertility

Eligibility Criteria

Criteria

• Ages Eligible for Study: 20 Years to 45 Years
• Sexes Eligible for Study: Male
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• men with clinical varicoceles underwent microsurgical varicocelectomy due to causes other than infertility such as testicular pain, discomfort or scrotal mass

Exclusion Criteria:

• adolescents

• men with proven fertility or azoospermia

• men with preoperative normal sperm analysis

• available data to compare between preoperative and postoperative semen analyses

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Seoul National University Hospital	Seoul		Korea, Republic of	110-744

Sponsors and Collaborators

• Seoul National University Hospital

Investigators

• Study Chair: Soo Woong Kim, M.D.,Ph.D., Seoul National University Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Soo Woong Kim, MD, Professor, Seoul National University Hospital
• ClinicalTrials.gov Identifier: NCT02006316
• Other Study ID Numbers: SeoulNUH
• First Posted: Dec 10, 2013
• Last Update Posted: May 14, 2014
• Last Verified: May 1, 2014

• Additional relevant MeSH terms: Infertility; Varicocele

Study Results

No Results Posted as of May 14, 2014