Cervical Vestibular Evoked Myogenic Potentials in Recurrent and Persistant Benign Paroxysmal Positional Vertigo
Study Details
Study Description
Brief Summary
The goal of this observational study is to compare the cervical vestibular evoked myogenic potentials in recurrent/persistant BPPV and nonrecurrent BPPV. Recurrent/persistant BPPV is considered as the patients who require more than one repositioning manuever for the resolution of symptoms and the recurrent cases in the first three months after the diagnosis.
The main question[s] it aims to answer are:
-
Is there any difference between the cVEMP findings of diseased ears of recurrent and nonrecurrent BPPV cases?
-
Is there any difference between the cVEMP findings of diseased ears and healthy ears of BPPV patients
-
Is there any difference between the cVEMP findings of healthy ears of recurrent and nonrecurrent BPPV cases and healthy controls?
Patients with VNG confirmed BPPV will be recruited and CVEMP test will be performed before the therapeutic manuevers.
Control visits will be scheduled on the 7th day after the therateutic menuevers are performed.
Patients will be followed-up for 4 weeks after the resolution of symptoms. Researchers will compare recurrent (Group 1), nonrecurrent (group 2) BPPV patients and healthy controls (Group 3) to see if there is any difference between the cVEMP findings of two groups.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Group 1 Patients with recurrent BPPV |
Device: Cervical VEMP testing
cervical vestibular evoked myogenic potentials
|
| Group 2 Patients with non recurrent BPPV |
Device: Cervical VEMP testing
cervical vestibular evoked myogenic potentials
|
| Group 3 Healthy controls |
Device: Cervical VEMP testing
cervical vestibular evoked myogenic potentials
|
Outcome Measures
Primary Outcome Measures
- The findings of cVEMP test which was performed 4 weeks after the resolution of BPPV symptoms [13 weeks]
Patients with VNG confirmed BPPV will be recruited and CVEMP test will be performed before the therapeutic manuevers. Control visits will be scheduled on the 7th day after the therateutic menuevers are performed. Patients will be followed-up for 4 weeks after the resolution of symptoms. Researchers will compare recurrent (Group 1), nonrecurrent (group 2) BPPV patients and healthy controls (Group 3) to see if there is any difference between the cVEMP findings of these groups.
Eligibility Criteria
Criteria
Inclusion Criteria:
- Patients admitted to ENT clinic with unilateral posterior or lateral canal BPPV for the first time
Exclusion Criteria:
-
patients with bilateral BPPV
-
patients with recurrent or resistant BPPV
-
patients with spontaneous nystagmus
-
vestibular or neurologic disorders other than BPPV
-
patients who use medication which may affect the vestibular system or muscle tone
-
cervical muscle disorders and ocular pathologies which may affect the VEMP results
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Haseki Training and Research Hospital | İstanbul | Turkey | 34096 |
Sponsors and Collaborators
- Haseki Training and Research Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Karatas A, Yuce T, Cebi IT, Acar Yuceant G, Haci C, Salviz M. Evaluation of Cervical Vestibular-Evoked Myogenic Potential Findings in Benign Paroxysmal Positional Vertigo. J Int Adv Otol. 2016 Dec;12(3):316-320. doi: 10.5152/iao.2016.2170. Epub 2016 Aug 1.
- Kim EJ, Oh SY, Kim JS, Yang TH, Yang SY. Persistent otolith dysfunction even after successful repositioning in benign paroxysmal positional vertigo. J Neurol Sci. 2015 Nov 15;358(1-2):287-93. doi: 10.1016/j.jns.2015.09.012. Epub 2015 Sep 5.
- Vaduva C, Esteban-Sanchez J, Sanz-Fernandez R, Martin-Sanz E. Prevalence and management of post-BPPV residual symptoms. Eur Arch Otorhinolaryngol. 2018 Jun;275(6):1429-1437. doi: 10.1007/s00405-018-4980-x. Epub 2018 Apr 23.
- Xu H, Liang FY, Chen L, Song XC, Tong MC, Thong JF, Zhang QQ, Sun Y. Evaluation of the utricular and saccular function using oVEMPs and cVEMPs in BPPV patients. J Otolaryngol Head Neck Surg. 2016 Feb 9;45:12. doi: 10.1186/s40463-016-0125-7.
- Yetiser S, Ince D, Gul M. An analysis of vestibular evoked myogenic potentials in patients with benign paroxysmal positional vertigo. Ann Otol Rhinol Laryngol. 2014 Oct;123(10):686-95. doi: 10.1177/0003489414532778. Epub 2014 May 1.
- cVEMP in intractable BPPV