AlcoolPredict: Risk Factors Associated With Binge Drinking Behaviors Among College Students

Sponsor

CHU de Reims (Other)

Overall Status

Completed

CT.gov ID

NCT02794311

Collaborator

(none)

125

Enrollment

Location

55.7

Duration (Months)

2.2

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to specify the psychological, cognitive, neuro-functional and genetic profile associated with binge drinker behaviors among young adults. Results will help identifying more precisely vulnerability factors associated with this pattern of alcohol consumption and guiding prevention efforts.

Condition or Disease	Intervention/Treatment	Phase
Binge Drinking	Other: Alcoolpredict	N/A

Detailed Description

Binge drinking behavior is characterised by speed of drinking on a particular occasion, frequency of drunkenness during the most recent six month period, and the percentage of times getting drunk when drinking. The prevalence of weekly binge drinking among European Union drinkers in 2009 was reported to be 28% of the student population, and 33% among all young people aged 15-24. The consequences of this behavior are multiple and often dramatic, they include: academic failure, violent acts, rape, domestic or road accidents. The study aims to identify vulnerability factors associated with binge drinking. The protocol explores the psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI) patterns associated with binge drinking behavior.

Study Design

Study Type:

Interventional

Actual Enrollment :

125 participants

Allocation:

N/A

Intervention Model:

Single Group Assignment

Masking:

None (Open Label)

Primary Purpose:

Health Services Research

Official Title:

AlcoholPredict: Neuropsychology, Brain Imaging and Genetic Polymorphisms in Binge Drinking

Study Start Date :

Feb 1, 2015

Actual Primary Completion Date :

Sep 24, 2019

Actual Study Completion Date :

Sep 24, 2019

Outcome Measures

Primary Outcome Measures

Neuropsychological test : Mini International Neuropsychiatric Interview (M.I.N.I) [day 1]
Neuropsychological test : Wisconsin Card Sorting Test (WCST) [V2(3 weeks later)]
Genetics tests (Single Nucleotide Polymorphism) [V2(3 weeks later)]
MRI - signal BOLD (" Blood Oxygen Level Dependant "). [V3(up to 2 month)]
Neuropsychological test : Family Informant Schedule and Criteria (FISC) [day 1]
Neuropsychological test : Alcohol Use Questionnaire [day 1]
Neuropsychological test :Trail Making Test, partie A et B [V3(up to 2 month)]
Neuropsychological test : Plus/Minus Test [V3(up to 2 month)]
Neuropsychological test :Go/No-Go [V3(up to 2 month)]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 25 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion criteria :

Males or females
Right-handed
Aged 18-25 years
Native French speaker, able to read French and complete study evaluations
Caucasian
Able to provide informed written and verbal consent

Exclusion criteria

A significant general medical illness, including neurological disorders, mental retardation or head trauma
Depression, bipolar disorder, schizophrenia or schizoaffective disorder diagnostic according to DSM-IV
Handling of psychotropics substances
A sensorial impairment (visual and/or hearing)
Women who are pregnant
Contraindication to the use of MRI (pacemaker, metal in their body)

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Chu Reims	Reims		France	51092

Sponsors and Collaborators

CHU de Reims

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

CHU de Reims

ClinicalTrials.gov Identifier:

NCT02794311

Other Study ID Numbers:

PO13129

First Posted:

Jun 9, 2016

Last Update Posted:

Jun 12, 2020

Last Verified:

Jun 1, 2020

Additional relevant MeSH terms:

Binge Drinking

Study Results

No Results Posted as of Jun 12, 2020