Biobank For MS And Other Demyelinating Diseases

Sponsor

Accelerated Cure Project for Multiple Sclerosis (Other)

Overall Status

Active, not recruiting

CT.gov ID

NCT00445367

Collaborator

(none)

3,226

Enrollment

Locations

365

Duration (Months)

322.6

Patients Per Site

0.9

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

To establish a large, longitudinal collection of high quality samples and data from subjects with MS, selected other demyelinating diseases (Transverse Myelitis (TM), Neuromyelitis Optica (NMO) or Devic's, Acute Disseminated Encephalomyelitis (ADEM), and Optic Neuritis (ON)), and related and unrelated unaffected controls. Samples and data will be available as a shared resource to scientists researching the causes, sub-types, and biomarkers of MS and related demyelinating diseases.

Condition or Disease	Intervention/Treatment	Phase
Multiple Sclerosis Transverse Myelitis Neuromyelitis Optica Acute Disseminated Encephalomyelitis Optic Neuritis

Study Design

Study Type:

Observational

Actual Enrollment :

3226 participants

Observational Model:

Case-Control

Time Perspective:

Other

Official Title:

Large-scale, Multi-disciplinary Sample and Data Repository for Multiple Sclerosis and Related Demyelinating Diseases

Study Start Date :

May 1, 2006

Anticipated Primary Completion Date :

Oct 1, 2026

Anticipated Study Completion Date :

Oct 1, 2036

Arms and Interventions

Arm	Intervention/Treatment
Case
Control

Outcome Measures

Primary Outcome Measures

Eligibility Criteria

Criteria

Ages Eligible for Study:

N/A and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

age 18+ able to give informed consent or individuals younger than 18 with parental permission and able to give assent
willing to provide up to 110 ml (50 ml for < 18 years old) of blood via venipuncture
experienced at least one CNS demyelinating event characteristic of MS, TM, NMO, ADEM, or ON

Exclusion Criteria:

history of blood borne pathogens
allogeneic bone marrow transplant
clinical or radiological evidence of stroke, meningitis, or other well characterized diseases of the nervous system (with the exception of MS, TM, NMO, ADEM, or ON).
weight less than 37 pounds

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Barrow Neurological Institute	Phoenix	Arizona	United States	85013
2	Stanford University	Stanford	California	United States	94305
3	The Rocky Mountain MS Center at Anschutz Medical Campus at UC Denver	Aurora	Colorado	United States	80045
4	Shepherd Center	Atlanta	Georgia	United States	30309
5	Johns Hopkins	Baltimore	Maryland	United States	21287
6	Beth Israel Deaconess	Boston	Massachusetts	United States	02215
7	University of Massachusetts Medical School	Worcester	Massachusetts	United States	01605
8	Multiple Sclerosis Research Center of New York	New York	New York	United States	10019
9	The Ohio State University	Columbus	Ohio	United States	43210
10	University of Texas Southwestern Medical Center at Dallas	Dallas	Texas	United States	76051