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Study of Biomarker From Blood and Tissue of Head and Neck Carcinoma

Sponsor
Southern Medical University, China (Other)
Overall Status
Unknown status
CT.gov ID
NCT01171235
Collaborator
(none)
200
Enrollment
29
Duration (Months)

Study Details

Study Description

Brief Summary

The aim of the study is to find for one or more serum or tissue markers of molecular biology in head and neck cancer patients used for early diagnosis, predicting prognosis and being sensitive to chemotherapy and radiotherapy

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Head and neck malignant tumors, especially nasopharyngeal carcinoma in southern China with the high incidence, its incidence, treatment, prognosis or tumor markers in serum has been a hot research with little progress.In our study, we collect NPC-based collection including the blood samples of laryngeal, hypopharyngeal cancer, separating serum and white blood cells stored in -80 degrees，while tissues are frozen in liquid nitrogen and embedded in paraffin。 Patient treatment and prognosis are combined in order to find for markers of molecular biology used for early diagnosis, predicting prognosis and being sensitive to chemotherapy and radiotherapy.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    200 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Study of Previously Collected Blood and Tissue Samples From Patients With Nasopharyngeal Carcinoma,Laryngeal Carcinoma and Hypopharyngeal Carcinoma
    Study Start Date :
    Jul 1, 2010
    Anticipated Primary Completion Date :
    Dec 1, 2011
    Anticipated Study Completion Date :
    Dec 1, 2012

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      15 Years to 75 Years
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      No
      Inclusion Criteria:

      • all of nasopharyngeal carcinoma

      • hypopharyngeal carcinoma or laryngeal carcinoma visited at ENT department of NanFang hospital

      Exclusion Criteria:
      • all of above patients whose anticipated survival duration were less than 6 months

      Contacts and Locations

      Locations

      No locations specified.

      Sponsors and Collaborators

      • Southern Medical University, China

      Investigators

      • Study Director: Ping Xiang Li, doctor, E.N.T department of NanFang hospital

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT01171235
      Other Study ID Numbers:
      • NFYY-H&N-1
      First Posted:
      Jul 28, 2010
      Last Update Posted:
      Jul 28, 2010
      Last Verified:
      Mar 1, 2009
      Keywords provided by , ,
      Laryngeal Neoplasms
      Pharyngeal Neoplasms
      Additional relevant MeSH terms:
      Neoplasms
      Laryngeal Neoplasms
      Pharyngeal Neoplasms

      Study Results

      No Results Posted as of Jul 28, 2010