Biomarkers, TCM Body Constitution, Dietary Pattern and Psychological Factors in Predicting Depression Among University Students
This study aims to determine the predictors of depression among university students in Universiti Tunku Abdul Rahman (UTAR) Sungai Long Campus.
|Condition or Disease||Intervention/Treatment||Phase|
University students are a high at risk group for development of depression. Identifying the determinants of depression could help in the diagnosis and treatment of this disorder. This study will incorporate questionnaire and blood sample data collection procedures on 397 subjects. Written consent will be obtained from the subjects. Eligible subjects will be given self-administered questionnaires which include Patient health questionnaire (PHQ-9), Constitution in Chinese medicine questionnaire (CCMQ), Dysfunctional Attitude Scale (DAS), Depression Anxiety Stress Scales (DASS-21) - stress and anxiety subscales, Perceived stress scale-10 (PSS-10), Rosenberg self-esteem scale (RSES), and Food frequency questionnaire (FFQ). Once the subjects completed the questionnaires, blood samples will be collected from them by a trained phlebotomist. In addition, 10 most high at risk of depression subjects (with PHQ-9 scores 10 and above) and 10 healthy subjects (with PHQ-9 scores lower than 10) will be selected randomly for protein expression to further identify the proteins that significantly expressed among them.
Arms and Interventions
University students in Universiti Tunku Abdul Rahman Sungai Long Campus
Primary Outcome Measures
- Genetic, TCM body constitution, psychological factors and dietary pattern are significant predictors for depression among university students. [Baseline]
Univariate and multivariate logistic regression will be performed.
Secondary Outcome Measures
- Prevalence of depression among university students. [Baseline]
Patient Health Questionnaire (PHQ-9): Non depressed = 0 - 9; Depressed = 10 - 27
- Protein significantly expressed between depressed and non-depressed students. [Baseline]
Liquid chromatography-mass spectrometry (LC-MS) will be performed.
Able to read and communicate in English
Special education disability (deaf and blind)
History of infectious diseases
Contacts and Locations
|1||Universiti Tunku Abdul Rahman||Kajang||Selangor||Malaysia||43000|
Sponsors and Collaborators
- Universiti Tunku Abdul Rahman
- Principal Investigator: Chai Nien Foo, Universiti Tunku Abdul Rahman
Study Documents (Full-Text)None provided.