Current_ONB: Current Intensity for the Obturator Nerve Block
Study Details
Study Description
Brief Summary
The purpose of the present study was to find out the difference in current intensity required for nerve stimulation according to the presence or absence of neuromuscular blockade during the obturator nerve block procedure for TURP.
Condition or Disease | Intervention/Treatment | Phase |
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N/A |
Detailed Description
During the transurethral resection of bladder tumors (TURBT) procedure under spinal anesthesia, the obturator nerve block is required to prevent the accidental movement of adductor longus muscles by electrical stimulation. However, during general anesthesia, the contraction of the adductor longus muscle would be lost due to deep neuromuscular blockade. However, some reports showed that the contraction of the adductor longus muscle occurs even in the deep neuromuscular blockade.
The current intensity for the nerve stimulation during nerve block is 0.3--0.5 mA when the needle tip is near the nerve. However, it is still unknown what current intensity is required to show the contraction of the adductor longus muscle when the patient is in a deep neuromuscular blockade.
Therefore, in this study, investigators aimed to determine the difference in current intensity required for nerve stimulation according to the presence or absence of neuromuscular blockade during obturator nerve block for TURP. In addition, investigators aimed to determine that the obturator nerve block is required during the TURP procedure in patients with deep neuromuscular blockade during general anesthesia.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Experimental: Current intensity An I-gel mask is inserted for the mechanical ventilator of the patient who is sedated with propofol. For the ultrasound-guided obturator nerve (ON) block, and needle tip gradually advanced to the anterior branch of the ON. The current intensity for the stimulation of ON starts at 1.0 mA (using the sequential electrical nerve stimulation mode), and the needle is advanced gradually to the location where the contraction of the adductor longus muscle (ALM) occurs at 0.3-0.5 mA. After fixing the needle in that position, measure the current intensity. Then, rocuronium (0.6 mg/kg) is administered under quantitative neuromuscular-blockade monitoring. When the train-of-four count becomes 0, the current intensity is increased until the contraction of the ALM occurs. The current intensity is measured when the contraction of the ALM occurs. |
Drug: Rocuronium Bromide
After measuring the initial current intensity, quantitative neuromuscular blockade monitoring is applied, and rocuronium (0.6 mg/kg) is administered.
Other Names:
Diagnostic Test: Nerve stimulator
Measuring the minimum current intensity for the stimulation of the obturator nerve to show the contraction of the adductor longus muscle.
Other Names:
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Outcome Measures
Primary Outcome Measures
- Initial current intensity [About 5 minutes after starting obturator nerve block procedure]
The current intensity for the stimulation of the obturator nerve starts at 1.0 mA (using the sequential electrical nerve stimulation mode), and the needle is advanced gradually to the location where the stimulus response occurs at 0.3-0.5 mA. After fixing the needle position in a position where contraction of the adductor longus muscle responds to the minimum current intensity, measure the current intensity.
- Final current intensity [About 10 minutes after starting obturator nerve block procedure]
After administration of rocuronium (0.6 mg/kg), when the train-of-four count becomes 0, the current intensity for the stimulation of the obturator nerve is increased until the contraction of the adductor longus muscle occurs. The current intensity is measured when the contraction of the adductor longus muscle occurs.
Secondary Outcome Measures
- Current intensity after the administration of rocuronium (0.6 mg/kg) [Between 5 minutes and 10 minutes after starting obturator nerve block procedure]
After administration of rocuronium (0.6 mg/kg), the quantitative neuromuscular blockade monitoring using train-of-four is observed with 12 seconds interval. At each time point, the current intensity for the obturator nerve is increased until the contraction of the adductor longus muscle occurs. The current intensity at each time point is measured.
Eligibility Criteria
Criteria
Inclusion Criteria:
- Patients undergoing TURP procedure
Exclusion Criteria:
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Patients with anatomical or functional anomaly in the upper airways
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Patients with neuromuscular disease
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Patients with hip joint disorders
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BMI of < 18.5 or > 30.0 kg/m2
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Chosun University Hospital | Gwangju | Korea, Republic of | 61453 |
Sponsors and Collaborators
- Chosun University Hospital
Investigators
- Study Chair: Ki Tae Jung, M.D., Ph.D., Chosun University Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
- ONB