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Blood Characteristics and Abdominal Emergency Surgery

Sponsor
University of Chile (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT06028854
Collaborator
(none)
40
Enrollment
1
Location
15
Anticipated Duration (Months)
2.7
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

After surgical tissue damage, cellular blood components are involved in tissue repair processes, yet their preoperative characteristics are not considered in routine clinical practice.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Surgical injuries initiate the recruitment of cellular blood components for tissue repair. Baseline inflammation levels and cellular response to tissue damage are absent from perioperative management algorithms despite their importance in regeneration. This project seeks to examine patients preoperative parameters before surgery and evaluate if there is a correlation with clinical outcomes.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    40 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Association Between Preoperative Blood Characteristics and Mortality in Abdominal Emergency Surgeries
    Anticipated Study Start Date :
    Sep 15, 2023
    Anticipated Primary Completion Date :
    Oct 15, 2024
    Anticipated Study Completion Date :
    Dec 15, 2024

    Arms and Interventions

    Arm Intervention/Treatment
    High Neutrophil count

    Patients with high neutrophil count in their preoperative complete blood count
    Low Neutrophil count

    Patients with low neutrophil count in their preoperative complete blood count

    Outcome Measures

    Primary Outcome Measures

    1. Death [1 year]

      The number of deceased patients.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 65 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
      1. Patients between 18 and 65 years of age at the time of surgery. b) Patients with acute intra-abdominal pathology requiring emergency surgery. c) Complete blood count performed in the emergency department of our center within the 24 hours prior to surgery.
    Exclusion Criteria:
      1. Patients who are users of anticoagulation prior to admission for any reason; b) Patients who have had previous hospitalization or surgery in the last 6 months.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Hospital Clínico de la Universidad de Chile Independencia Santiago Chile 8380456

    Sponsors and Collaborators

    • University of Chile

    Investigators

    • Study Chair: Felipe Maldonado, Hospital Clinico de la Universidad de Chile

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University of Chile
    ClinicalTrials.gov Identifier:
    NCT06028854
    Other Study ID Numbers:
    • OAIC 1337/23
    First Posted:
    Sep 8, 2023
    Last Update Posted:
    Sep 8, 2023
    Last Verified:
    Aug 1, 2023
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Emergencies
    Surgical Wound

    Study Results

    No Results Posted as of Sep 8, 2023