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Effects of Blood Flow Restriction During Eccentric Resistance Exercise

Sponsor
Utah State University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05606744
Collaborator
(none)
45
Enrollment
2
Arms
9
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

The purpose of this study is to compare the muscle strength and muscle soreness effects experienced following short term (acute) eccentric exercise with and without blood flow restriction (BFR) performed at low - moderate training intensities.

Condition or Disease Intervention/Treatment Phase
  • Device: Eccentric exercise / Eccentric exercise with blood flow restriction
 N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
45 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
Individuals will be randomly assigned to a BFR or non BFR exercise condition. The subjects will perform a single, 3-5 minute bout of eccentric exercise on the Eccentron device either with BFR (with restriction cuffs on the thigh per the procedures below) or without the BFR.Individuals will be randomly assigned to a BFR or non BFR exercise condition. The subjects will perform a single, 3-5 minute bout of eccentric exercise on the Eccentron device either with BFR (with restriction cuffs on the thigh per the procedures below) or without the BFR.
Masking:
Single (Investigator)
Primary Purpose:
Other
Official Title:
Effects of Blood Flow Restriction During Multiple-joint Eccentric Resistance Training on Muscle Morphology and Function of the Lower Body
Anticipated Study Start Date :
Jun 1, 2023
Anticipated Primary Completion Date :
Dec 1, 2023
Anticipated Study Completion Date :
Mar 1, 2024

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: Eccentric exercise

Only multi-joint eccentric exercise

Device: Eccentric exercise / Eccentric exercise with blood flow restriction
Individuals will be randomized to receive eccentric exercise only, or eccentric exercise with blood flow restriction.
Experimental: Eccentric training with blood flow restriction

Multi-joint eccentric exercise with blood flow restriction

Device: Eccentric exercise / Eccentric exercise with blood flow restriction
Individuals will be randomized to receive eccentric exercise only, or eccentric exercise with blood flow restriction.

Outcome Measures

Primary Outcome Measures

  1. visual analog scale (soreness) [Baseline (pretest)]

    soreness

  2. visual analog scale (soreness) [immediately post exercise]

    soreness

  3. visual analog scale (soreness) [24 hours post exercise]

    soreness

  4. visual analog scale (soreness) [48 hours post exercise]

    soreness

  5. visual analog scale (soreness) [72 hours post exercise]

    soreness

  6. force algometer (soreness) [Baseline (pretest)]

    soreness

  7. force algometer (soreness) [immediately post exercise]

    soreness

  8. force algometer (soreness) [24 hours post exercise]

    soreness

  9. force algometer (soreness) [48 hours post exercise]

    soreness

  10. force algometer (soreness) [72 hours post exercise]

    soreness

Secondary Outcome Measures

  1. Eccentric muscle strength [Baseline (pretest)]

    muscle strength will be assessed on the Eccentron.

  2. Eccentric muscle strength [immediately post exercise]

    muscle strength will be assessed on the Eccentron.

  3. Eccentric muscle strength [24 hours post exercise]

    muscle strength will be assessed on the Eccentron.

  4. Eccentric muscle strength [48 hours post exercise]

    muscle strength will be assessed on the Eccentron.

  5. Eccentric muscle strength [72 hours post exercise]

    muscle strength will be assessed on the Eccentron.

  6. Single-leg hop [Baseline (pretest)]

    3 single-leg hops per limb

  7. Single-leg hop [immediately post exercise]

    3 single-leg hops per limb

  8. Single-leg hop [24 hours post exercise]

    3 single-leg hops per limb

  9. Single-leg hop [48 hours post exercise]

    3 single-leg hops per limb

  10. Single-leg hop [72 hours post exercise]

    3 single-leg hops per limb

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 30 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Exclusion Criteria:

  • lower body surgery or injury in the last 12 months

  • have any neuromuscular disease

  • height >76 inches tall

  • height <54 inches tall

  • eccentric strength greater than 725 pounds

  • pregnant or plan to be pregnant in the duration of the protocol

  • don't do resistance exercise at least once per week

  • perform intense cardio or strength training >4 days per week

  • Present with any other significant comorbid conditions that would impair the ability to participate in the exercise-based testing

Inclusion criteria:

  • 18 - 30 years old

  • strength train lower body 1-3 times per week

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Utah State University

Investigators

  • Principal Investigator: Brennan Thompson, PhD, Utah State University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Brennan Thompson, Associate Professor, Utah State University
ClinicalTrials.gov Identifier:
NCT05606744
Other Study ID Numbers:
  • 12042a
First Posted:
Nov 7, 2022
Last Update Posted:
Nov 7, 2022
Last Verified:
Nov 1, 2022
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No

Study Results

No Results Posted as of Nov 7, 2022