Bowel Preparation Before 3D Rectal Water Contrast Transvaginal Ultrasonography for Rectosigmoid Endometriosis
Study Details
Study Description
Brief Summary
Three-dimensional (3D) rendering may be employed during transvaginal rectal water-contrast transvaginal ultrasonography (RWC-TVS) for detecting the presence and describe the characteristics of rectosigmoid endometriosis. This study aims to evaluate the impact of bowel preparation on the diagnostic parameters of 3D-RWC-TVS in women with suspicion of rectosigmoid endometriosis.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
An accurate diagnosis of the presence, location and extent of the rectosigmoid endometriosis is of paramount importance for the clinicians in order to inform the patients on the potential surgical or medical treatments. It is well established that transvaginal ultrasonography is the first-line investigation in patients with suspicion of deep infiltrating endometriosis. An improvement in the performance of transvaginal ultrasonography in diagnosing rectosigmoid endometriosis may be obtained by using rectal water contrast during transvaginal ultrasonographic scan. In the last years, three-dimensional (3D) rendering has been employed during transvaginal ultrasound for benign gynecological diseases.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Patients with suspicion of rectosigmoid endometriosis
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Procedure: 3D-RWC-TVS with bowel preparation
Rectal water contrast transvaginal ultrasonography is based on the distention of rectosigmoid with saline solution. Three-dimensional reconstructions convert standard 2D grayscale ultrasound acquisitions into a volumetric dataset.
Bowel preparation is based on a low-residue diet given in the two days before the examination and a rectal enema administered a few hours before the procedure.
Procedure: 3D-RWC-TVS without bowel preparation
Rectal water contrast transvaginal ultrasonography is based on the distention of rectosigmoid with saline solution. Three-dimensional reconstructions convert standard 2D grayscale ultrasound acquisitions into a volumetric dataset.
|
Outcome Measures
Primary Outcome Measures
- To compare the accuracy of 3D-RWC-TVS with and without bowel preparation in the diagnosis of rectosigmoid endometriosis. [At maximum 6 months before laparoscopic surgical approach]
The results of imaging will be compared with surgical and histological findings.
Secondary Outcome Measures
- To compare the precision of 3D-RWC-TVS with and without bowel preparation in estimating the length (mid-sagittal diameter) of the rectosigmoid endometriotic nodules [At maximum 6 months before laparoscopic surgical approach]
The results of imaging will be compared with surgical and histological findings.
- To compare the accuracy of 3D-RWC-TVS with and without bowel preparation in the diagnosis of multifocal rectosigmoid endometriosis. [At maximum 6 months before laparoscopic surgical approach]
The results of imaging will be compared with surgical and histological findings.
Eligibility Criteria
Criteria
Inclusion Criteria:
- pain and intestinal symptoms suggestive of rectosigmoid endometriosis
Exclusion Criteria:
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previous surgical diagnosis of intestinal endometriosis
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previous radiological diagnosis of intestinal endometriosis (based on Magnetic Resonance or double-contrast barium enema
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history of colorectal surgery (except appendectomy)
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contraindications to bowel preparation or computed colonography (such as non-- compliant patients and rectal malformations)
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previous bilateral ovariectomy
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psychiatric disorders
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | IRCCS Ospedale Policlinico San Martino | Genova | Italy |
Sponsors and Collaborators
- Piazza della Vittoria 14 Studio Medico - Ginecologia e Ostetricia
Investigators
- Study Director: Simone Ferrero, MD, PhD, IRRCS Ospedale Policlinico San Martino
Study Documents (Full-Text)
None provided.More Information
Publications
- Ferrero S, Barra F, Stabilini C, Vellone VG, Leone Roberti Maggiore U, Scala C. Does Bowel Preparation Improve the Performance of Rectal Water Contrast Transvaginal Ultrasonography in Diagnosing Rectosigmoid Endometriosis? J Ultrasound Med. 2019 Apr;38(4):1017-1025. doi: 10.1002/jum.14790. Epub 2018 Sep 24.
- Ferrero S, Scala C, Stabilini C, Vellone VG, Barra F, Leone Roberti Maggiore U. Transvaginal sonography with vs without bowel preparation in diagnosis of rectosigmoid endometriosis: prospective study. Ultrasound Obstet Gynecol. 2019 Mar;53(3):402-409. doi: 10.1002/uog.19194. Epub 2019 Feb 6.
- BP-3DRWC-TVS-RECTOSIG