Vinorelbine in Treating Children With Recurrent or Refractory Cancers
Sponsor
Children's Oncology Group (Other)
Overall Status
Completed
CT.gov ID
NCT00003234
Collaborator
National Cancer Institute (NCI) (NIH)
50
228
3
106
0.2
0
Study Details
Study Description
Brief Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of vinorelbine in treating children with recurrent or refractory cancer.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 2 |
Detailed Description
OBJECTIVES: I. Determine the response rate of children with recurrent or refractory malignancies treated with vinorelbine. II. Assess the toxic effects of this drug in these children.
OUTLINE: Patients receive vinorelbine IV over 6-10 minutes weekly on weeks 1-6. Treatment repeats every 8 weeks for a total of 10 courses in the absence of disease progression or unacceptable toxicity. Patients are followed every 4 months for 2 years, every 6 months for 1 year, and then annually thereafter.
PROJECTED ACCRUAL: A maximum of 100 patients will be accrued for this study within 2 years.
Study Design
Study Type:
Interventional
Actual Enrollment
:
50 participants
Primary Purpose:
Treatment
Official Title:
A Phase II Study of Navelbine (Vinorelbine) In Children With Recurrent Or Refractory Malignancies
Study Start Date
:
May 1, 1998
Actual Primary Completion Date
:
Mar 1, 2006
Actual Study Completion Date
:
Mar 1, 2007
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Stratum 1 - Soft Tissue Sarcoma See detailed description. |
Drug: vinorelbine tartrate
Other Names:
|
| Experimental: Stratum 2 - CNS Tumors See detailed description. |
Drug: vinorelbine tartrate
Other Names:
|
| Experimental: Stratum 3 - Neuroblastoma See detailed description. |
Drug: vinorelbine tartrate
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Disease progression []
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
to 21 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
DISEASE CHARACTERISTICS: Histologically confirmed recurrent or refractory solid malignant tumors of childhood including: Soft tissue sarcoma Rhabdomyosarcoma Nonrhabdomyosarcoma Extraosseous Ewing's sarcoma CNS tumors Astrocytoma Primitive neuroectodermal tumor Atypical teratoid/rhabdoid tumors Ependymoma Recurrent neuroblastoma Measurable disease No more than 2 prior treatment regimens
PATIENT CHARACTERISTICS: Age: 21 and under at diagnosis Performance status: ECOG 0-2 Life expectancy: At least 2 months Hematopoietic: For patients with solid tumors (unless marrow involvement): Absolute neutrophil count (ANC) at least 1000/mm3 Platelet count at least 100,000/mm3 (transfusion independent) Hemoglobin at least 10 g/dL (RBC transfusions allowed) For patients post bone marrow transplantation: ANC at least 1,000/mm3 Platelet count at least 50,000/mm3 (transfusion independent) Hemoglobin at least 10 g/dL (RBC transfusions allowed) Hepatic: Total bilirubin no greater than 1.5 times normal SGOT/SGPT less than 2.5 times normal Renal: Creatinine no greater than 1.5 times normal OR Creatinine clearance or radioisotope glomerular filtration rate at least 70 mL/min Neurologic: Seizure disorder allowed if well controlled CNS toxicity no greater than grade 2
PRIOR CONCURRENT THERAPY: Biologic therapy: At least 6 months since prior bone marrow transplantation No concurrent immunomodulating agents Chemotherapy: At least 2 weeks since prior chemotherapy (4 weeks for nitrosourea) and recovered No other concurrent chemotherapy Endocrine therapy: No concurrent corticosteroids except for increased intracranial pressure due to CNS tumors Radiotherapy: At least 6 months since prior radiotherapy to craniospinal axis, spine, and/or more than 50% of the bony pelvis Concurrent radiotherapy to localized painful lesions allowed if at least one measurable lesion is not in radiation field Surgery: Not specified Other: No concurrent participation in another CCG, POG, or COG therapeutic study
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | United States | 35294-3300 |
| 2 | University of South Alabama Medical Center | Mobile | Alabama | United States | 36617-2293 |
| 3 | Phoenix Children's Hospital | Phoenix | Arizona | United States | 85006 |
| 4 | Arizona Cancer Center | Tucson | Arizona | United States | 85724 |
| 5 | University of Arkansas for Medical Sciences | Little Rock | Arkansas | United States | 72205 |
| 6 | Southern California Permanente Medical Group | Downey | California | United States | 90242 |
| 7 | Cancer Center and Beckman Research Institute, City of Hope | Duarte | California | United States | 91010-3000 |
| 8 | University of California San Diego Cancer Center | La Jolla | California | United States | 92093-0658 |
| 9 | Loma Linda University Medical Center | Loma Linda | California | United States | 92354 |
| 10 | Jonathan Jaques Children's Cancer Center | Long Beach | California | United States | 90801-1428 |
| 11 | Children's Hospital Los Angeles | Los Angeles | California | United States | 90027-0700 |
| 12 | Cedars-Sinai Medical Center | Los Angeles | California | United States | 90048 |
| 13 | Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | United States | 90095-1781 |
| 14 | Valley Children's Hospital | Madera | California | United States | 93638 |
| 15 | Children's Hospital of Oakland | Oakland | California | United States | 94609 |
| 16 | Chao Family Comprehensive Cancer Center | Orange | California | United States | 92868 |
| 17 | Children's Hospital of Orange County | Orange | California | United States | 92868 |
| 18 | Lucile Packard Children's Hospital at Stanford | Palo Alto | California | United States | 94304 |
| 19 | Sutter Cancer Center | Sacramento | California | United States | 95816 |
| 20 | University of California Davis Medical Center | Sacramento | California | United States | 95817 |
| 21 | Kaiser Permanente-Southern California Permanente Medical Group | San Diego | California | United States | 92120 |
| 22 | Children's Hospital and Health Center | San Diego | California | United States | 92123-4282 |
| 23 | Kaiser Permanente Medical Group - San Francisco | San Francisco | California | United States | 94115 |
| 24 | UCSF Cancer Center and Cancer Research Institute | San Francisco | California | United States | 94143-0128 |
| 25 | Santa Barbara Cottage Hospital | Santa Barbara | California | United States | 93102 |
| 26 | Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | United States | 95051-5386 |
| 27 | David Grant Medical Center | Travis Air Force Base | California | United States | 94535 |
| 28 | Childhood Hematology/Oncology Associates | Denver | Colorado | United States | 80218 |
| 29 | Children's Hospital of Denver | Denver | Colorado | United States | 80218 |
| 30 | Presbyterian-St Luke's Medical Center | Denver | Colorado | United States | 80218 |
| 31 | University of Connecticut Health Center | Farmington | Connecticut | United States | 06360-7106 |
| 32 | Yale Comprehensive Cancer Center | New Haven | Connecticut | United States | 06520-8028 |
| 33 | Alfred I. Dupont Institute | Wilmington | Delaware | United States | 19899 |
| 34 | Lombardi Cancer Center | Washington | District of Columbia | United States | 20007 |
| 35 | Children's National Medical Center | Washington | District of Columbia | United States | 20010-2970 |
| 36 | Walter Reed Army Medical Center | Washington | District of Columbia | United States | 20307-5000 |
| 37 | Broward General Medical Center | Fort Lauderdale | Florida | United States | 33316 |
| 38 | Children's Hospital of Southwest Florida | Fort Myers | Florida | United States | 33908 |
| 39 | Shands Hospital and Clinics, University of Florida | Gainesville | Florida | United States | 32610-100277 |
| 40 | Joe DiMaggio Children's Hospital at Memorial | Hollywood | Florida | United States | 33021 |
| 41 | Nemours Children's Clinic | Jacksonville | Florida | United States | 32207 |
| 42 | University of Miami-Jackson Memorial Hospital Medical Center | Miami | Florida | United States | 33136 |
| 43 | Miami Children's Hospital | Miami | Florida | United States | 33155 |
| 44 | Baptist Hospital of Miami | Miami | Florida | United States | 33176-2197 |
| 45 | Walt Disney Memorial Cancer Institute | Orlando | Florida | United States | 32803 |
| 46 | Nemours Children's Clinic-Orlando | Orlando | Florida | United States | 32806 |
| 47 | Sacred Heart Children's Hospital | Pensacola | Florida | United States | 32504 |
| 48 | All Children's Hospital | St. Petersburg | Florida | United States | 33701 |
| 49 | Tampa Children's Hospital | Tampa | Florida | United States | 33677-4227 |
| 50 | St. Mary's Hospital | West Palm Beach | Florida | United States | 33407 |
| 51 | Emory University Hospital - Atlanta | Atlanta | Georgia | United States | 30322 |
| 52 | Children's Healthcare of Atlanta - Scottish Rite | Atlanta | Georgia | United States | 30342 |
| 53 | Medical College of Georgia Comprehensive Cancer Center | Augusta | Georgia | United States | 30912-4000 |
| 54 | Medical Center of Central Georgia | Macon | Georgia | United States | 31201 |
| 55 | Memorial Health University Medical Center, Inc. | Savannah | Georgia | United States | 31403-3089 |
| 56 | Cancer Research Center of Hawaii | Honolulu | Hawaii | United States | 96813 |
| 57 | Tripler Army Medical Center | Honolulu | Hawaii | United States | 96859-5000 |
| 58 | Mountain States Tumor Institute | Boise | Idaho | United States | 83712 |
| 59 | Rush-Presbyterian-St. Luke's Medical Center | Chicago | Illinois | United States | 60612 |
| 60 | University of Illinois at Chicago | Chicago | Illinois | United States | 60612 |
| 61 | Children's Memorial Hospital, Chicago | Chicago | Illinois | United States | 60614 |
| 62 | University of Chicago Cancer Research Center | Chicago | Illinois | United States | 60637-1470 |
| 63 | Hope Children's Hospital | Oak Lawn | Illinois | United States | 60453 |
| 64 | Lutheran General Hospital | Park Ridge | Illinois | United States | 60068 |
| 65 | Saint Jude Midwest Affiliate | Peoria | Illinois | United States | 61637 |
| 66 | University Child Health Services Clinic | Rockford | Illinois | United States | 61104 |
| 67 | Southern Illinois University School of Medicine | Springfield | Illinois | United States | 62794-9230 |
| 68 | Indiana University Cancer Center | Indianapolis | Indiana | United States | 46202-5289 |
| 69 | St. Vincent Hospital and Health Care Center | Indianapolis | Indiana | United States | 46260 |
| 70 | Raymond Blank Memorial Hospital for Children | Des Moines | Iowa | United States | 50308 |
| 71 | John Stoddard Cancer Center | Des Moines | Iowa | United States | 50309 |
| 72 | Holden Comprehensive Cancer Center at The University of Iowa | Iowa City | Iowa | United States | 52242-1009 |
| 73 | Wesley Medical Center | Wichita | Kansas | United States | 67214 |
| 74 | Albert B. Chandler Medical Center, University of Kentucky | Lexington | Kentucky | United States | 40536-0084 |
| 75 | Kosair Children's Hospital | Louisville | Kentucky | United States | 40232 |
| 76 | Tulane University School of Medicine | New Orleans | Louisiana | United States | 70112 |
| 77 | Children's Hospital of New Orleans | New Orleans | Louisiana | United States | 70118 |
| 78 | Ochsner Clinic | New Orleans | Louisiana | United States | 70121 |
| 79 | Eastern Maine Medical Center | Bangor | Maine | United States | 04401 |
| 80 | Maine Children's Cancer Program | Scarborough | Maine | United States | 04074 |
| 81 | Marlene & Stewart Greenebaum Cancer Center, University of Maryland | Baltimore | Maryland | United States | 21201 |
| 82 | Sinai Hospital of Baltimore | Baltimore | Maryland | United States | 21225 |
| 83 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | United States | 21231-2410 |
| 84 | Boston Floating Hospital Infants and Children | Boston | Massachusetts | United States | 02111 |
| 85 | Dana-Farber Cancer Institute | Boston | Massachusetts | United States | 02115 |
| 86 | Baystate Medical Center | Springfield | Massachusetts | United States | 01199 |
| 87 | University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | United States | 01655 |
| 88 | Mott Children's Hospital | Ann Arbor | Michigan | United States | 48109 |
| 89 | Children's Hospital of Michigan | Detroit | Michigan | United States | 48201 |
| 90 | Henry Ford Hospital | Detroit | Michigan | United States | 48202 |
| 91 | St. John Hospital and Medical Center | Detroit | Michigan | United States | 48236 |
| 92 | Michigan State University | East Lansing | Michigan | United States | 48824 |
| 93 | Hurley Medical Center | Flint | Michigan | United States | 48503 |
| 94 | Spectrum Health and DeVos Children's Hospital | Grand Rapids | Michigan | United States | 49503 |
| 95 | Bronson Methodist Hospital | Kalamazoo | Michigan | United States | 49007 |
| 96 | William Beaumont Hospital | Royal Oak | Michigan | United States | 48073 |
| 97 | Duluth Clinic | Duluth | Minnesota | United States | 55805 |
| 98 | Children's Hospitals and Clinics - Minneapolis | Minneapolis | Minnesota | United States | 55404 |
| 99 | Mayo Clinic Cancer Center | Rochester | Minnesota | United States | 55905 |
| 100 | Children's Hospitals and Clinics of Minnesota | Saint Paul | Minnesota | United States | 55102 |
| 101 | University of Mississippi Medical Center | Jackson | Mississippi | United States | 39216-4505 |
| 102 | Children's Mercy Hospital | Kansas City | Missouri | United States | 64108 |
| 103 | Cardinal Glennon Children's Hospital | Saint Louis | Missouri | United States | 63104 |
| 104 | St. Louis Children's Hospital | Saint Louis | Missouri | United States | 63110 |
| 105 | Children's Hospital of Omaha | Omaha | Nebraska | United States | 68114 |
| 106 | University of Nebraska Medical Center | Omaha | Nebraska | United States | 68198-3330 |
| 107 | Sunrise Hospital and Medical Center | Las Vegas | Nevada | United States | 89109-2306 |
| 108 | Norris Cotton Cancer Center | Lebanon | New Hampshire | United States | 03756-0002 |
| 109 | Hackensack University Medical Center | Hackensack | New Jersey | United States | 07601 |
| 110 | Cancer Institute of New Jersey | New Brunswick | New Jersey | United States | 08901 |
| 111 | Newark Beth Israel Medical Center | Newark | New Jersey | United States | 07112 |
| 112 | St. Joseph's Hospital and Medical Center | Paterson | New Jersey | United States | 07503 |
| 113 | Atlantic Health System | Summit | New Jersey | United States | 07901 |
| 114 | University of New Mexico School of Medicine | Albuquerque | New Mexico | United States | 87131 |
| 115 | Cancer Center of Albany Medical Center | Albany | New York | United States | 12208 |
| 116 | Montefiore Medical Center | Bronx | New York | United States | 10467-2490 |
| 117 | Brooklyn Hospital Center | Brooklyn | New York | United States | 11201 |
| 118 | State University of New York Health Science Center at Brooklyn College of Medicine | Brooklyn | New York | United States | 11203 |
| 119 | Brookdale University Hospital and Medical Center | Brooklyn | New York | United States | 11212 |
| 120 | Maimonides Medical Center | Brooklyn | New York | United States | 11219 |
| 121 | Roswell Park Cancer Institute | Buffalo | New York | United States | 14263-0001 |
| 122 | North Shore University Hospital | Manhasset | New York | United States | 11030 |
| 123 | Schneider Children's Hospital | New Hyde Park | New York | United States | 11042 |
| 124 | Memorial Sloan-Kettering Cancer Center | New York | New York | United States | 10021 |
| 125 | New York Presbyterian Hospital - Cornell Campus | New York | New York | United States | 10021 |
| 126 | Mount Sinai School of Medicine | New York | New York | United States | 10029 |
| 127 | Columbia Presbyterian Hospital | New York | New York | United States | 10032 |
| 128 | University of Rochester Cancer Center | Rochester | New York | United States | 14642 |
| 129 | State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | United States | 11790-7775 |
| 130 | State University of New York - Upstate Medical University | Syracuse | New York | United States | 13210 |
| 131 | New York Medical College | Valhalla | New York | United States | 10595 |
| 132 | Mission Saint Joseph's Health System | Asheville | North Carolina | United States | 28801 |
| 133 | Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | United States | 27599-7295 |
| 134 | Carolinas Medical Center | Charlotte | North Carolina | United States | 28232-2861 |
| 135 | Presbyterian Healthcare | Charlotte | North Carolina | United States | 28233-3549 |
| 136 | Duke Comprehensive Cancer Center | Durham | North Carolina | United States | 27710 |
| 137 | East Carolina University School of Medicine | Greenville | North Carolina | United States | 27858-4354 |
| 138 | Dakota Cancer Institute | Fargo | North Dakota | United States | 58108-6001 |
| 139 | Children's Hospital Medical Center of Akron | Akron | Ohio | United States | 44308 |
| 140 | Children's Hospital Medical Center - Cincinnati | Cincinnati | Ohio | United States | 45229-3039 |
| 141 | Ireland Cancer Center | Cleveland | Ohio | United States | 44106-5065 |
| 142 | Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | United States | 44195 |
| 143 | Children's Hospital of Columbus | Columbus | Ohio | United States | 43205-2696 |
| 144 | Children's Medical Center - Dayton | Dayton | Ohio | United States | 45404 |
| 145 | Toledo Children's Hospital | Toledo | Ohio | United States | 43601 |
| 146 | St. Vincent Mercy Medical Center | Toledo | Ohio | United States | 43608 |
| 147 | Forum Health-Tod Childrens Hospital | Youngstown | Ohio | United States | 44501 |
| 148 | Children's Hospital of Oklahoma | Oklahoma City | Oklahoma | United States | 73104 |
| 149 | Natalie Warren Bryant Cancer Center | Tulsa | Oklahoma | United States | 74136 |
| 150 | Doernbecher Children's Hospital | Portland | Oregon | United States | 97201-3098 |
| 151 | Legacy Emanuel Hospital and Health Center | Portland | Oregon | United States | 97227 |
| 152 | Geisinger Medical Center | Danville | Pennsylvania | United States | 17822-2001 |
| 153 | Milton S. Hershey Medical Center | Hershey | Pennsylvania | United States | 17033-0850 |
| 154 | Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | United States | 19104 |
| 155 | St. Christopher's Hospital for Children | Philadelphia | Pennsylvania | United States | 19134-1095 |
| 156 | Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | United States | 15213 |
| 157 | Rhode Island Hospital | Providence | Rhode Island | United States | 02903 |
| 158 | Medical University of South Carolina | Charleston | South Carolina | United States | 29425-0721 |
| 159 | Center for Cancer Treatment and Research | Columbia | South Carolina | United States | 29203 |
| 160 | Children's Hospital of Greenville Hospital System | Greenville | South Carolina | United States | 29605 |
| 161 | Avera Cancer Institute | Sioux Falls | South Dakota | United States | 57105 |
| 162 | Sioux Valley Hospital | Sioux Falls | South Dakota | United States | 57117 |
| 163 | James H. Quillen College of Medicine | Johnson City | Tennessee | United States | 37614-0622 |
| 164 | East Tennessee Children's Hospital | Knoxville | Tennessee | United States | 37901 |
| 165 | Saint Jude Children's Research Hospital | Memphis | Tennessee | United States | 38105-2794 |
| 166 | Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | United States | 37232-6838 |
| 167 | Texas Tech University Health Sciences Center School of Medicine | Amarillo | Texas | United States | 79106 |
| 168 | Children's Hospital of Austin | Austin | Texas | United States | 78701 |
| 169 | Medical City Dallas Hospital | Dallas | Texas | United States | 75230 |
| 170 | Simmons Cancer Center - Dallas | Dallas | Texas | United States | 75235-9154 |
| 171 | Cook Children's Medical Center - Fort Worth | Fort Worth | Texas | United States | 76104 |
| 172 | University of Texas Medical Branch | Galveston | Texas | United States | 77555-0209 |
| 173 | University of Texas - MD Anderson Cancer Center | Houston | Texas | United States | 77030-4009 |
| 174 | Baylor College of Medicine | Houston | Texas | United States | 77030 |
| 175 | San Antonio Military Pediatric Cancer and Blood Disorders Center | Lackland Air Force Base | Texas | United States | 78236-5300 |
| 176 | Covenant Children's Hospital | Lubbock | Texas | United States | 79410 |
| 177 | Methodist Health Care System | San Antonio | Texas | United States | 78229 |
| 178 | University of Texas Health Science Center at San Antonio | San Antonio | Texas | United States | 78284-7811 |
| 179 | Scott and White Memorial Hospital | Temple | Texas | United States | 76508 |
| 180 | Vermont Cancer Center | Burlington | Vermont | United States | 05401-3498 |
| 181 | Cancer Center at the University of Virginia | Charlottesville | Virginia | United States | 22908 |
| 182 | Inova Fairfax Hospital | Falls Church | Virginia | United States | 22042-3300 |
| 183 | Children's Hospital of the King's Daughters | Norfolk | Virginia | United States | 23507 |
| 184 | Naval Medical Center, Portsmouth | Portsmouth | Virginia | United States | 23708-2197 |
| 185 | Massey Cancer Center | Richmond | Virginia | United States | 23298-0037 |
| 186 | Carilion Roanoke Community Hospital | Roanoke | Virginia | United States | 24013 |
| 187 | Children's Hospital and Regional Medical Center - Seattle | Seattle | Washington | United States | 98105 |
| 188 | Fred Hutchinson Cancer Research Center | Seattle | Washington | United States | 98109-1024 |
| 189 | Group Health Cooperative of Puget Sound | Seattle | Washington | United States | 98112 |
| 190 | Deaconess Medical Center | Spokane | Washington | United States | 99210-0248 |
| 191 | Mary Bridge Children's Health Center | Tacoma | Washington | United States | 98405 |
| 192 | Madigan Army Medical Center | Tacoma | Washington | United States | 98431-5000 |
| 193 | West Virginia University - Charleston | Charleston | West Virginia | United States | 25302 |
| 194 | Cabell-Huntington Hospital, Inc | Huntington | West Virginia | United States | 25701 |
| 195 | West Virginia University Hospitals | Morgantown | West Virginia | United States | 26506-9300 |
| 196 | Bellin Memorial Hospital | Green Bay | Wisconsin | United States | 54301 |
| 197 | St. Vincent Hospital | Green Bay | Wisconsin | United States | 54307-3508 |
| 198 | Gundersen Lutheran Medical Center | La Crosse | Wisconsin | United States | 54601 |
| 199 | University of Wisconsin Hospital and Clinics | Madison | Wisconsin | United States | 53792-0001 |
| 200 | Midwest Children's Cancer Center | Milwaukee | Wisconsin | United States | 53226 |
| 201 | Sydney Children's Hospital | Randwick | New South Wales | Australia | 2031 |
| 202 | Children's Hospital at Westmead | Westmead | New South Wales | Australia | 2145 |
| 203 | Royal Children's Hospital | Brisbane | Queensland | Australia | 4029 |
| 204 | Royal Children's Hospital | Parkville | Victoria | Australia | 3052 |
| 205 | Princess Margaret Hospital for Children | Perth | Western Australia | Australia | 6001 |
| 206 | Alberta Children's Hospital | Calgary | Alberta | Canada | T2T 5C7 |
| 207 | Cross Cancer Institute | Edmonton | Alberta | Canada | T6G 1Z2 |
| 208 | British Columbia Children's Hospital | Vancouver | British Columbia | Canada | V6H 3V4 |
| 209 | CancerCare Manitoba | Winnipeg | Manitoba | Canada | R3E 0V9 |
| 210 | Janeway Children's Health and Rehabilitation Centre | St. John's | Newfoundland and Labrador | Canada | A1A 1R8 |
| 211 | IWK Health Centre | Halifax | Nova Scotia | Canada | B3J 3G9 |
| 212 | Children's Hospital | Hamilton | Ontario | Canada | L8N 3Z5 |
| 213 | Children's Hospital of Western Ontario | London | Ontario | Canada | N6C 2V5 |
| 214 | Children's Hospital of Eastern Ontario | Ottawa | Ontario | Canada | K1H 8L1 |
| 215 | Hospital for Sick Children | Toronto | Ontario | Canada | M5G 1X8 |
| 216 | McGill University Health Center - Montreal Children's Hospital | Montreal | Quebec | Canada | H3H 1P3 |
| 217 | Hopital Sainte Justine | Montreal | Quebec | Canada | H3T 1C5 |
| 218 | Centre Hospitalier de L'Universite Laval | Sainte Foy | Quebec | Canada | GIV 4G2 |
| 219 | Laval University Medical Center | Sainte-Foy | Quebec | Canada | G1V 4G2 |
| 220 | Allan Blair Cancer Centre | Regina | Saskatchewan | Canada | S4T 7T1 |
| 221 | Saskatoon Cancer Centre | Saskatoon | Saskatchewan | Canada | S7N 4H4 |
| 222 | Academisch Ziekenhuis Groningen | Groningen | Netherlands | 9713 EZ | |
| 223 | Starship Children's Hospital | Auckland | New Zealand | ||
| 224 | University of Puerto Rico School of Medicine Medical Sciences Campus | San Juan | Puerto Rico | 00936-5067 | |
| 225 | San Jorge Childrens Hospital | Santurce | Puerto Rico | 00912 | |
| 226 | Swiss Pediatric Oncology Group Bern | Bern | Switzerland | CH 3010 | |
| 227 | Swiss Pediatric Oncology Group Geneva | Geneva | Switzerland | CH 1211 | |
| 228 | Swiss Pediatric Oncology Group Lausanne | Lausanne | Switzerland | CH 1011 |
Sponsors and Collaborators
- Children's Oncology Group
- National Cancer Institute (NCI)
Investigators
- Study Chair: John F. Kuttesch, PhD, MD, M.D. Anderson Cancer Center
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Children's Oncology Group
ClinicalTrials.gov Identifier:
NCT00003234
Other Study ID Numbers:
- A09705
- COG-A09705
- CCG-09705
- CDR0000066106
First Posted:
Oct 28, 2003
Last Update Posted:
Jul 28, 2014
Last Verified:
Jul 1, 2014
Keywords provided by Children's Oncology Group
Additional relevant MeSH terms: