Clincosm LogoSign in Get a demo

Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome

Sponsor
Shin Kong Wu Ho-Su Memorial Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT02179905
Collaborator
(none)
69
Enrollment
1
Location
8
Duration (Months)
8.6
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study is to analyze the relationship between brain structure, the heart rate variability and the serum fatty acid component of the irritable bowel syndrome patients.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Several studies showed that the gray matter and white matter of the brain related to the symptoms of irritable bowel syndrome patients.

    The investigators study is to analyse the relationship between thickness of cortex of irritable patients, the sympathetic tone and the serum fatty acid component of the irritable bowel syndrome patients. It is to clarify the mechanism of irritable bowel syndrome, whether the symptoms of irritable bowel syndrome are related to the thickness of cortex or inflammation status of the body.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    69 participants
    Observational Model:
    Case-Control
    Official Title:
    Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome
    Study Start Date :
    Jan 1, 2013
    Actual Primary Completion Date :
    Sep 1, 2013
    Actual Study Completion Date :
    Sep 1, 2013

    Arms and Interventions

    Arm Intervention/Treatment
    Irritable bowel syndrome, Control

    Outcome Measures

    Primary Outcome Measures

    1. The relationship between brain structure, heart rate variability and fatty acid of the irritable bowel syndrome patients. [Patients who suffered from IBS for more than 5 years.]

    Secondary Outcome Measures

    1. The relationship between thickness of brain cortex and the symptoms of irritable bowel syndrome [Patients who suffered from IBS for more than 5 years.]

    Other Outcome Measures

    1. The relationship between heart rate variability and symptoms of irritable bowel syndrome patients. [Patients who suffered from IBS for more than 5 years.]

    2. The relationship between component of fatty acid and symptoms of irritable bowel syndrome patients. [Patients who suffered from IBS for more than 5 years.]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    20 Years to 50 Years
    Sexes Eligible for Study:
    Female
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • female

    • between 20 and 50 years old

    • meet Rome III criteria

    Exclusion Criteria:

    • colon and small intestinal disease

    • psychiatric disease patients

    • patients received major surgery in the past 5 years

    • diabetic patients

    • patients with metal implant

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Shin Kong Wu Ho-Su Memorial Hospital Taipei Taiwan 111

    Sponsors and Collaborators

    • Shin Kong Wu Ho-Su Memorial Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Shin Kong Wu Ho-Su Memorial Hospital
    ClinicalTrials.gov Identifier:
    NCT02179905
    Other Study ID Numbers:
    • SKH-8302-102-DR-14
    First Posted:
    Jul 2, 2014
    Last Update Posted:
    Jul 2, 2014
    Last Verified:
    Jun 1, 2014
    Keywords provided by Shin Kong Wu Ho-Su Memorial Hospital
    MRI
    Heart rate variability
    Fatty acid
    Additional relevant MeSH terms:
    Irritable Bowel Syndrome
    Syndrome

    Study Results

    No Results Posted as of Jul 2, 2014