The Brain Processes Underlying Speech Motor Learning and Speech Production

Sponsor

Arizona State University (Other)

Overall Status

Recruiting

CT.gov ID

NCT05918679

Collaborator

National Institute on Deafness and Other Communication Disorders (NIDCD) (NIH)

510

Enrollment

Location

Anticipated Duration (Months)

13.4

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The aim of this research is to develop protocols that selectively target and improve speech-motor learning processes. Participants will be asked to name pictures, read words/sentences, and listen to sounds while their speech signals will be collected during the study.

Condition or Disease	Intervention/Treatment	Phase
Healthy Adults	Behavioral: Effects of speech variability on speech motor learning Behavioral: Effects of error-detection training on speech motor learning Behavioral: Contributions of error awareness to speech motor learning Behavioral: Enhancing auditory-to-motor mapping with augmented visual feedback Behavioral: Effects of enhanced auditory-motor awareness on speech motor learning

Study Design

Study Type:

Observational

Anticipated Enrollment :

510 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Improving Speech Motor Learning Processes Using Augmented Behavioral Interventions

Anticipated Study Start Date :

Jun 1, 2023

Anticipated Primary Completion Date :

Aug 1, 2026

Anticipated Study Completion Date :

Aug 1, 2026

Arms and Interventions

Arm	Intervention/Treatment
Healthy Adults	Behavioral: Effects of speech variability on speech motor learning This intervention will examine whether reducing normal variability of speech could improve error detection and speech motor learning. We will design training tasks to change subjects' speech variability. We will train subjects to decrease/decrease their speech variability. Upon completing the training tasks, subjects will complete a motor learning task. Behavioral: Effects of error-detection training on speech motor learning This intervention will examine whether improving subjects' ability to detect and estimate auditory perturbation could improve speech motor learning. For this purpose, we will design training tasks to change subjects' estimation of the perturbation magnitude. After completing the training tasks, subjects will complete the motor learning task. Behavioral: Contributions of error awareness to speech motor learning This intervention will examine the contributions of error awareness to speech motor learning. Subjects will produce a target word while receiving perturbed auditory feedback with different magnitudes. Subjects will be trained to indicate the magnitude of the error they perceived with or without visual feedback. Behavioral: Enhancing auditory-to-motor mapping with augmented visual feedback This intervention will determine the contributions of enhanced auditory-to-motor mappings to speech motor learning. We will design training tasks in which we will use visual feedback to provide feedback regarding subjects' accuracy of auditory-to-motor mapping. Behavioral: Effects of enhanced auditory-motor awareness on speech motor learning In this intervention, subjects will be trained to control their articulators more accurately and be more aware of their articulators' position and their auditory consequences. After the training tasks, subjects will complete a motor learning task.

Arm

Intervention/Treatment

Healthy Adults

Behavioral: Effects of speech variability on speech motor learning

This intervention will examine whether reducing normal variability of speech could improve error detection and speech motor learning. We will design training tasks to change subjects' speech variability. We will train subjects to decrease/decrease their speech variability. Upon completing the training tasks, subjects will complete a motor learning task.

Behavioral: Effects of error-detection training on speech motor learning

This intervention will examine whether improving subjects' ability to detect and estimate auditory perturbation could improve speech motor learning. For this purpose, we will design training tasks to change subjects' estimation of the perturbation magnitude. After completing the training tasks, subjects will complete the motor learning task.

Behavioral: Contributions of error awareness to speech motor learning

This intervention will examine the contributions of error awareness to speech motor learning. Subjects will produce a target word while receiving perturbed auditory feedback with different magnitudes. Subjects will be trained to indicate the magnitude of the error they perceived with or without visual feedback.

Behavioral: Enhancing auditory-to-motor mapping with augmented visual feedback

This intervention will determine the contributions of enhanced auditory-to-motor mappings to speech motor learning. We will design training tasks in which we will use visual feedback to provide feedback regarding subjects' accuracy of auditory-to-motor mapping.

Behavioral: Effects of enhanced auditory-motor awareness on speech motor learning

In this intervention, subjects will be trained to control their articulators more accurately and be more aware of their articulators' position and their auditory consequences. After the training tasks, subjects will complete a motor learning task.

Outcome Measures

Primary Outcome Measures

Change in speech output in response to previously experienced auditory errors [within each session of the study that may last up to 2 hours]
In each trial, participants will experience an auditory error while they produce speech (e.g., they may say "head" but hear "had"). Participants' speech will be measured in each trial. The investigators will measure how the participants' speech changes due to auditory errors experienced in previous trials.
Change In Speech Output Immidiately After Hearing Auditory Errors [within each session of the study that may last up to 2 hours]
In each trial, participants will experience an auditory error while they produce speech (e.g., they may say "head" but hear "had"). The investigators will measure how the participants' speech changes due to auditory errors that they experience in the current trial.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Inclusion Criteria:

18 years and older
native speaker of American English
normal (age-appropriate) binaural pure-tone hearing threshold
not taking medications affecting sensorimotor functioning
no current or history of communication, neurological, or psychological disorders

Exclusion Criteria:

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Arizona State University	Tempe	Arizona	United States	85287

Sponsors and Collaborators

Arizona State University
National Institute on Deafness and Other Communication Disorders (NIDCD)

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Arizona State University

ClinicalTrials.gov Identifier:

NCT05918679

Other Study ID Numbers:

STUDY00017657
R01DC019905

First Posted:

Jun 26, 2023

Last Update Posted:

Jun 26, 2023

Last Verified:

Jun 1, 2023

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Study Results

No Results Posted as of Jun 26, 2023